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http://dx.doi.org/10.1136/archdischild-2023-326051 | DOI Listing |
Org Lett
September 2025
Department of Chemistry, Indiana University, 800 East Kirkwood Avenue, Bloomington, Indiana 47405-7102, United States.
This communication describes a straightforward method for the trifluoromethylborylation of unactivated alkenes. The reaction proceeds through the formation of an electron donor-acceptor (EDA) complex between a trifluoromethylthiophenium salt and bis(catechol)diboron under broad-spectrum white-light irradiation. Due to the mild reaction conditions, the trifluoromethylborylation tolerates a wide range of functional groups, including esters, acids, alcohols, epoxides, and a variety of heterocycles.
View Article and Find Full Text PDFBull Math Biol
September 2025
Department of Mathematics, Siena University, 515 Loudon Road, Loudonville, NY, 12211, USA.
Autonomous differential equation compartmental models hold broad utility in epidemiology and public health. However, these models typically cannot account explicitly for myriad factors that affect the trajectory of infectious diseases, with seasonal variations in host behavior and environmental conditions as noteworthy examples. Fortunately, using non-autonomous differential equation compartmental models can mitigate some of these deficiencies, as the inclusion of time-varying parameters can account for temporally varying factors.
View Article and Find Full Text PDFChaos
September 2025
The Key Laboratory of Intelligent Computing and Signal Processing of Ministry of Education, School of Internet, Anhui University, Hefei 230601, China.
A captivating challenge in network research is the reconstruction of complex network structures from limited binary-state time series data. Although some reconstruction approaches based on dynamical rules or sparse system of linear equations have been proposed, these approaches either rely on known dynamical rules, limiting their generality, or the system of linear equations is often empirically determined, with weak interpretability and the performance being sensitive to parameter settings. To address these limitations, we propose a network reconstruction method based on linearization grounded in mean-field approximation.
View Article and Find Full Text PDFJ Virol
September 2025
Department of Microbiology and Immunology, Center for Pathogen Research, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Unlabelled: There is a need for the development of broad-spectrum antiviral compounds that can act as first-line therapeutic countermeasures to emerging viral infections. Host-directed approaches present a promising avenue of development and carry the benefit of mitigating risks of viral escape mutants. We have previously found the SKI (super killer) complex to be a broad-spectrum, host-target with our lead compound ("UMB18") showing activity against influenza A virus, coronaviruses, and filoviruses.
View Article and Find Full Text PDFSmall
September 2025
Jožef Stefan Institute, Jamova cesta 39, Ljubljana, SI-1000, Slovenia.
The demand for rapid, field-deployable detection of hazardous substances has intensified the search for plasmonic sensors with both high sensitivity and fabrication simplicity. Conventional approaches to plasmonic substrates, however, often rely on lithographic precision or complex chemistries limiting scalability and reproducibility. Here, a facile, one-step synthesis of vertically aligned 2D nanosheets composed of intergrown CuO/CuO crystallites is presented, fabricated via oxygen plasma discharge on copper substrates.
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