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Purpose: The objective of this study was to evaluate the accuracy and effectiveness of an artificial intelligence (AI) program in identifying dental conditions using panoramic radiographs (PRs), as well as to assess the appropriateness of its treatment recommendations.
Material And Methods: PRs from 100 patients (representing 4497 teeth) with known clinical examination findings were randomly selected from a university database. Three dentomaxillofacial radiologists and the Diagnocat AI software evaluated these PRs. The evaluations were focused on various dental conditions and treatments, including canal filling, caries, cast post and core, dental calculus, fillings, furcation lesions, implants, lack of interproximal tooth contact, open margins, overhangs, periapical lesions, periodontal bone loss, short fillings, voids in root fillings, overfillings, pontics, root fragments, impacted teeth, artificial crowns, missing teeth, and healthy teeth.
Results: The AI demonstrated almost perfect agreement (exceeding 0.81) in most of the assessments when compared to the ground truth. The sensitivity was very high (above 0.8) for the evaluation of healthy teeth, artificial crowns, dental calculus, missing teeth, fillings, lack of interproximal contact, periodontal bone loss, and implants. However, the sensitivity was low for the assessment of caries, periapical lesions, pontic voids in the root canal, and overhangs.
Conclusion: Despite the limitations of this study, the synthesized data suggest that AI-based decision support systems can serve as a valuable tool in detecting dental conditions, when used with PR for clinical dental applications.
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http://dx.doi.org/10.5624/isd.20230109 | DOI Listing |
Periodontol 2000
September 2025
Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Oral cancer is a major global health burden, ranking sixth in prevalence, with oral squamous cell carcinoma (OSCC) being the most common type. Importantly, OSCC is often diagnosed at late stages, underscoring the need for innovative methods for early detection. The oral microbiome, an active microbial community within the oral cavity, holds promise as a biomarker for the prediction and progression of cancer.
View Article and Find Full Text PDFClin Genet
September 2025
Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
LONP1 encodes a mitochondrial protease essential for protein quality control and metabolism. Variants in LONP1 are associated with a diverse and expanding spectrum of disorders, including Cerebral, Ocular, Dental, Auricular, and Skeletal anomalies syndrome (CODAS), congenital diaphragmatic hernia (CDH), and neurodevelopmental disorders (NDD), with some individuals exhibiting features of mitochondrial encephalopathy. We report 16 novel LONP1 variants identified in 16 individuals (11 with NDD, 5 with CDH), further expanding the clinical spectrum.
View Article and Find Full Text PDFJ Prosthet Dent
September 2025
Professor, Washington Dental Service Endowed Chair in Dentistry, and Chair, Department of Restorative Dentistry, School of Dentistry, University of Washington, Seattle, Wash.
A practical and novel technique used both in testing and in practice when tightening dental implant screw systems is described for determining the preload implant screw systems, which differs from traditional tightening procedures that are based solely on the application of a predetermined manufacturer specified torque value. Preload is the critical quantity for a reliable joint: about 90% of tightening torque goes into overcoming friction and the remaining amount, approximately 10%, goes into preload. Because of the heavy dependence of torque on friction, the actual preload achieved is subject to large variability of up ±35%, depending on surface conditions (dry, wet, or contaminated).
View Article and Find Full Text PDFMethods Cell Biol
September 2025
Department of Cell Biology and Histology, University of the Basque Country UPV/EHU, Leioa, Spain. Electronic address:
Human Dental Pulp Stem Cells (hDPSCs) represent a remarkable cell source for tissue engineering and regenerative medicine, offering significant potential for use in personalized medicine and autologous therapies. Decellularized extracellular matrix (ECM)-derived biological scaffolds show excellent properties for supporting cell delivery and growth in both in vitro and in vivo applications. These scaffolds provide essential biochemical cues that regulate cellular functions and offer a more accurate representation of the in vivo environment.
View Article and Find Full Text PDFJ Endod
September 2025
Endodontic Department,. Electronic address:
Introduction: This study evaluated the fatigue resistance of two Nickel-titanium (NiTi) engine-driven file systems with identical geometries and different heat treatments tested under static and dynamic conditions in simulated root canals.
Methods: Cyclic fatigue tests were conducted using ProTaper Universal (PTU) and ProTaper Gold (PTG) instruments with a curvature of 35° and a radius of 6 mm in both static and dynamic modes at body temperature using a customized cyclic fatigue testing device. The number of cycles to fracture (NCF) was recorded.