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Endoscopic airway optical coherence tomography (OCT) is a non-invasive and high resolution imaging modality for the diagnosis and analysis of airway-related diseases. During OCT imaging of the upper airway, in order to reliably characterize its 3D structure, there is a need to automatically detect the airway lumen contour, correct rotational distortion and perform 3D airway reconstruction. Based on a long-range endoscopic OCT imaging system equipped with a magnetic tracker, we present a fully automatic framework to reconstruct the 3D upper airway model with correct bending anatomy. Our method includes an automatic segmentation method for the upper airway based on dynamic programming algorithm, an automatic initial rotation angle error correction method for the detected 2D airway lumen contour, and an anatomic bending method combined with the centerline detected from the magnetically tracked imaging probe. The proposed automatic reconstruction framework is validated on experimental datasets acquired from two healthy adults. The result shows that the proposed framework allows the full automation of 3D airway reconstruction from OCT images and thus reveals its potential to improve analysis efficiency of endoscopic OCT images.
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http://dx.doi.org/10.1364/BOE.496812 | DOI Listing |
J Appl Physiol (1985)
September 2025
Ludwig Engel Centre for Respiratory Research, Westmead Hospital, Sydney, NSW, Australia.
Lung volume change modifies pharyngeal airway patency by altering breathing-related passive force transmission between lower and upper airways (via tracheal and other connections). We hypothesise that such force transmission may also impact active upper airway dilator muscle function by altering resting muscle length. The aim of this study was to determine the relationship between end expiratory lung volume (EELV) and ability of sternohyoid muscle (SH) contraction to alter pharyngeal airway patency.
View Article and Find Full Text PDFLaryngoscope
September 2025
UCSF Voice & Swallowing Center, Department of Otolaryngology-Head and Neck Surgery, University of California, San Francisco, California, USA.
Objectives: In patients with significant upper airway stenosis, airway compromise can occur associated with general anesthesia (GA). A previous study demonstrated the feasibility of awake laser laryngeal stenosis surgery (ALLSS) in the operating room (OR) in five patients. This study sought to determine patient outcomes of ALLSS.
View Article and Find Full Text PDFNat Sci Sleep
September 2025
Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, People's Republic of China.
Aim: Obstructive sleep apnea (OSA) is characterized by repetitive upper airway collapse during sleep, resulting in frequent cortical arousals. However, currently used frequency-based arousal metrics do not sufficiently capture the heterogeneity and clinical significance of arousal responses. The odds ratio product (ORP) is a novel electroencephalographic marker that provides a continuous assessment of sleep depth and has the potential to serve as an objective measure of arousal intensity.
View Article and Find Full Text PDFMedicine (Baltimore)
September 2025
Department of Internal Medicine, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, Republic of Korea.
Rationale: Extranodal natural killer (NK)/T-cell lymphoma is an uncommon non-Hodgkin lymphoma, prevalent in Asia. It often involves the nasal and upper airway regions but can disseminate to other sites like skin, soft tissue, testis, and gastrointestinal tract, characterized by Epstein-Barr virus association.
Patient Concerns: This report discusses a 48-year-old male initially diagnosed with Behcet syndrome with dry mouth, uveitis, pruritic macules, and human leukocyte antigen-B51 positivity.
Medicine (Baltimore)
September 2025
Department of Cardiac Surgery, Chest Hospital, Tianjin University, Tianjin, China.
Rationale: Tracheomalacia, typically seen in relapsing polychondritis,[1] is rarely reported in association with congenital heart disease (CHD). In patients with pulmonary hypoperfusion-type CHD, surgical repair results in a rapid increase in pulmonary blood flow, predisposing them to mucus retention, airway obstruction, and respiratory distress. We describe acute airway collapse in a patient with double outlet right ventricle and congenital bronchial stenosis following cardiac repair.
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