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Patterns of so-called modern human behavior are increasingly well documented in an abundance of Middle Stone Age archaeological sites across southern Africa. Contextualized archives directly preceding the southern African Middle Stone Age, however, remain scarce. Current understanding of the terminal Acheulean in southern Africa derives from a small number of localities that are predominantly in the central and northern interior. Many of these localities are surface and deflated contexts, others were excavated prior to the availability of modern field documentation techniques, and yet other relevant assemblages contain low numbers of characteristic artifacts relative to volume of excavated deposit. The site of Montagu Cave, situated in the diverse ecosystem of the Cape Floral Region, South Africa, contains the rare combination of archaeologically rich, laminated and deeply stratified Acheulean layers followed by a younger Middle Stone Age occupation. Yet little is known about the site owing largely to a lack of contextual information associated with the early excavations. Here we present renewed excavation of Levels 21-22 at Montagu Cave, located in the basal Acheulean sequence, including new data on site formation and ecological context, geochronology, and technological variability. We document intensive occupation of the cave by Acheulean tool-producing hominins, likely at the onset of interglacial conditions in MIS 7. New excavations at Montagu Cave suggest that, while Middle Stone Age technologies were practiced by 300 ka in several other regions of Africa, the classic Acheulean persisted later in the Fynbos Biome of the southwestern Cape. We discuss the implications of this regionalized persistence for the biogeography of African later Middle Pleistocene hominin populations, for the ecological drivers of their technological systems, and for the pattern and pace of behavioral change just prior to the proliferation of the southern African later Middle Stone Age.
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http://dx.doi.org/10.1016/j.jhevol.2023.103435 | DOI Listing |
Charged hadron elliptic anisotropies (v_{2}) are presented over a wide transverse momentum (p_{T}) range for proton-lead (pPb) and lead-lead (PbPb) collisions at nucleon-nucleon center-of-mass energies of 8.16 and 5.02 TeV, respectively.
View Article and Find Full Text PDFJ Natl Med Assoc
September 2025
College of Medicine, 520W St NW, WA DC 20059, USA.
Background: Non-Hispanic African Americans were reported to have a higher rate of heat-related death than non-Hispanic whites. It is not known whether this racial disparity varies among US regions.
Methods: Multiple cause of death data were used to tabulate heat-related death records which listed ICD-10 codes X30 (exposure to excessive natural heat), P81.
PLoS One
September 2025
Department of Cardiology, Fuzhou University Affiliated Provincial Hospital, Fujian Provincial Hospital, Fuzhou, Fujian, China.
Introduction: Kidney stone disease is associated with numerous cardiovascular risk factors. However, the findings across studies are non-uniformly consistent, and the control of confounding variables remains suboptimal. This study aimed to investigate the association between kidney stone and cardiovascular disease.
View Article and Find Full Text PDFWorld J Urol
September 2025
Department of Clinical Laboratory, Fuzhou University Affiliated Provincial Hospital, Fuzhou, 350000, Fujian, China.
Objective: To develop and validate a prognostic nomogram for predicting the risk of proximal ureteral impacted calculi, supporting personalized clinical management.
Methods: This retrospective, multicenter study employed a continuous cohort of 391 patients with proximal ureteral stones treated between January 2021 and April 2024. Data from Longyan People's Hospital (affiliated with Xiamen Medical College) comprised the training set, while independent external validation was performed using data from The Fifth Affiliated Hospital of Fujian University of Traditional Chinese Medicine.
Arch Esp Urol
August 2025
Department of Urology, The Affiliated Hospital of Qingdao University, 266000 Qingdao, Shandong, China.
Background: Ureteroscopic lithotripsy using a semi-rigid ureteroscope is the standard treatment for urinary stones. Doxazosin-an alpha-1 adrenergic receptor blocker-relaxes ureteral smooth muscles, reducing peristalsis and contraction frequency. This study aimed to evaluate the efficacy and safety of adjunctive doxazosin before semi-rigid ureteroscopy and retrograde intrarenal surgery (RIRS) for urinary stones.
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