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Eight different cases are presented in this column, along with the lessons and principles that can be learned from each. The lessons and principles are general in nature and hence they are applicable to patients that readers will likely encounter.
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http://dx.doi.org/10.1097/PRA.0000000000000736 | DOI Listing |
Dose Response
September 2025
School of Pharmacy, Shujitsu University, Okayama-Shi, Japan.
Living organisms have been exposed to ionizing radiation throughout Earth's 4-billion-year history, with humans presently receiving about 2 mSv of ionizing radiation every year. While radiation generates reactive oxygen and nitrogen species (ROS and RNS), organisms have evolved mechanisms to neutralize these toxic molecules and utilize them as signal transducers. High doses of radiation are harmful, but low doses are seemingly essential, and moderate doses can provide benefits-a phenomenon known as hormesis.
View Article and Find Full Text PDFJ Cancer Educ
September 2025
Department of Health Sciences, Faculty of Public Health, Ubon Ratchathani Rajabhat University, Ubon Ratchathani, 34000, Thailand.
Cholangiocarcinoma (CCA) remains a major public health concern in Thailand, particularly in areas endemic for Opisthorchis viverrini infection. During the period of 2020-2022, there was a rapid shift in public communication behaviors that created new opportunities to promote health education through diverse media channels. This study aimed to assess public awareness of CCA prevention and explore the feasibility of applying social marketing strategies during a time of health crisis.
View Article and Find Full Text PDFPalliat Care Soc Pract
September 2025
Division of Psychiatry, Faculty of Brain Sciences, Univsersity College London, UK.
As rates of dementia increase, the need for care is clear. Understanding what this looks like and how people might orientate the narratives and practices of care against a universally relatable version of success is less clear cut yet seems crucial if we are to progress towards an ideal of care that allows for a 'good' or 'dignified' death with palliative care. With this as a central focus, the paper examines the orientating principles that govern the current approach to dementia care.
View Article and Find Full Text PDFClin Transl Oncol
September 2025
Catalonian Cancer Strategy, Department of Health, Biomedical Research Institute of Bellvitge (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.
Purpose: The Precision Oncology Program (POP) in Catalonia aims to provide equitable access to molecular testing for individuals with cancer, integrating Next-Generation Sequencing (NGS) into clinical practice to inform diagnosis, prognosis, and treatment decisions for both adult and pediatric patients with solid and hematologic malignancies, including somatic and germline alterations. This study evaluates the program's outcomes and impact.
Methods: This evaluation covers the period from the program's implementation in July 2021 through December 2023, with a more detailed analysis focusing on 2022-2023.
Stud Health Technol Inform
September 2025
Institute for Medical Informatics, Statistics, and Epidemiology, Leipzig University, Leipzig, Germany.
Introduction: In 2024, the GeMTeX project launched the largest ever de-identification campaign for German-language clinical reports, and, as a pilot study, published GraSCCoPHI, the first de-identified German-language gold standard corpus of synthetic discharge summaries.
Methods: GeMTeX's de-identification workflow is described here - including annotation tool management and, pre-annotation experience, such as assembling and training annotation groups and the evolution of guidelines.
Results: We present the project's progress in the first year with respect to de-identification efforts and the challenges we faced during the rollout at six hospital sites in four German states.