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In recent years, probiotics have been emerging as an attractive therapeutic strategy for several diseases. In orthopedics, probiotics seem to be a promising supplementation for treatment of osteoporosis, osteoarthritis, muscle loss-related disease, wound and ulcer issues, and prevention of surgical antibiotic prophylaxis side effects. Although probiotics are still not included in guidelines for these conditions, several studies have reported theoretical benefits of their administration. Further high-level clinical trials are necessary to convert research into solid clinical practice. However, probiotics represent a cost-effective future perspective and may play a role in association with traditional orthopedic therapies.
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http://dx.doi.org/10.3390/microorganisms11082021 | DOI Listing |
Water Res
September 2025
College of Hydrology and Water Resources, Hohai University, Nanjing 210098, China. Electronic address:
Groundwater overextraction presents persistent challenges due to strategic interdependence among decentralized users. While game-theoretic models have advanced the analysis of individual incentives and collective outcomes, most frameworks assume fully rational agents and neglect the role of cognitive and social factors. This study proposes a coupled model that integrates opinion dynamics with a differential game of groundwater extraction, capturing the interaction between institutional authority and evolving stakeholder preferences.
View Article and Find Full Text PDFJ Community Psychol
September 2025
Department of Behavioral, Social and Health Education Sciences, Rollins School of Public Health at Emory University, Atlanta, Georgia, USA.
Over the last decade, a range of research has demonstrated the detrimental impacts of policies criminalizing migration ("crimmigration") on Latinx mental health. In this study, we seek to examine youth perspectives on how crimmigration policies affect Latinx adolescents' connections to Latinx identity, culture, and communities and the implications for Latinx youth mental health. We explored how immigration enforcement policies affect Latinx youths' mental health using photovoice with ten youth in a high-deportation county in Atlanta in 2022.
View Article and Find Full Text PDFJ Med Chem
September 2025
School of Pharmacy, Hangzhou Normal University, Hangzhou 311121, PR China.
The prevalence of AGA is continuously rising, with an earlier age of onset. Currently, only minoxidil and finasteride have received FDA approval for the treatment of AGA, inadequately addressing the pressing clinical needs. Recently, the involvement of the Wnt/β-catenin signaling pathway in AGA has attracted increased research interest.
View Article and Find Full Text PDFCuad Bioet
September 2025
Universidad Católica de Murcia. Observatorio de Bioética de la Universidad Católica de Valencia. Carlos Albors, 34. 46220 Picassent
Although, in principle, the Lancet article Commission on Medicine, Nazism, and the Holocaust, aims to provide medical students with a moral compass to guide the future of medical practice as a social retaining wall against anti-Semitism, it deals with the Holocaust not from a philosophical point of view, but from a pedagogical one, resorting to didactic strategies from a historiographical approach. What seemed to be a plea against the behaviour of the Nazi doctors' experiments becomes a justification of the positive law of the liberal democracies in use. However, what it ignores is of the utmost importance: that the majority of the regime's doctors were tried and sentenced for their iniquitous actions, and yet, in contemporary Western society, an even greater danger is very much present: techno-science, which, as it stands, can once again compromise the identity, dignity and very life of the human person.
View Article and Find Full Text PDFJ Alzheimers Dis
September 2025
Institut des Sciences logopédiques, Faculté des Lettres et Sciences Humaines, University of Neuchâtel, Neuchâtel, Switzerland.
BackgroundThe production of verbal tenses is impaired in people with Alzheimer's disease (AD), as shown by several studies focusing on time reference and using sentence completion tasks. However, there is currently a limited understanding of how tense is produced in discourse with this disease. Discourse is interesting as it involves building a mental representation of the event to be narrated with its temporal framework and translating this framework into language using tense.
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