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| http://dx.doi.org/10.1016/j.jchf.2023.07.011 | DOI Listing |
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Semin Thorac Cardiovasc Surg
August 2025
Division of Cardiothoracic Surgery, Department of Surgery, University of Minnesota, Minneapolis, MN. Electronic address:
Biventricular heart failure remains a challenging issue in patients with end-stage cardiomyopathy requiring mechanical circulatory support options. Also, the Achilles heel of durable LVADs remains right ventricular failure that significantly impacts morbidity and mortality. With recent changes in the heart transplant allocation system, there has been major shifts in practice patterns in the use of ECMO, temporary VADs, and durable VADs in the treatment of biventricular failure and strategies for bridge to heart transplantation.
View Article and Find Full Text PDF[Anesthesia in patients with left ventricular assist devices : Anesthesiological management of patients with permanent left ventricular assist devices during noncardiac surgery].
Anaesthesiologie
August 2025
Universitätsklinikum Aachen, Pauwelsstraße 30, 52074, Aachen, Deutschland.
For patients with end-stage heart failure durable left ventricular assist devices (LVADs) are increasingly being used as an alternative to heart transplantation. Treatment with LVADs significantly improves both the survival rate and quality of life. The increasing prevalence of heart failure, particularly in older patients, combined with improved survival under LVAD therapy, has led to a growing population of LVAD recipients.
View Article and Find Full Text PDFSociété de Biomécanique Young Investigator Award: In silico study of the effects of Left Ventricular Assist Device inflow cannula design and pump unsteady flow on left ventricular hemodynamics.
J Biomech
September 2025
Mechanical Engineering, University of Washington, Seattle, WA, USA. Electronic address:
Advances in left ventricular assist devices (LVADs) have improved hemocompatibility and durability, making this technology a viable lifesaving long-term treatment option for individuals with advanced heart failure (HF). Despite these improvements, the rate of stroke in LVAD patients remains high. The inflow cannula design impacts Left Ventricle (LV) hemodynamics, potentially creating thrombogenic flow patterns.
View Article and Find Full Text PDFReducing driveline infection risk in durable mechanical circulatory support devices with ultra-flexible wires for energy transfer.
J Heart Lung Transplant
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Department of Mechanical and Process Engineering, Institute for Mechanical Systems, ETH Zurich, Zurich, Switzerland; Empa, Swiss Federal Laboratories for Material Science and Technology, Dübendorf, Switzerland.
Background: Driveline infections (DLIs) pose a burden to heart failure patients supported by durable mechanical circulatory support devices (dMCSs). A major factor to DLI comes from the low mechanical compliance of drivelines, affecting wound healing. New drivelines that mitigate mechanical stress on skin may reduce the risk of DLI.
View Article and Find Full Text PDFBackground And Aims: Right-side heart failure (RSHF) jeopardizes left ventricular assist device (LVAD) short- and long-term outcomes. The model for end-stage liver disease (MELD) score is an effective means of evaluating liver dysfunction. This study aims to investigate the predictive utility of preoperative MELD on post-LVAD implantation outcomes, specifically focusing on the incidence of RSHF.
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