Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
The judicious selection of 5,7-dibromo-2-methy-8-quinolinol (BQ) as a Mn(II) ionophore results in the synthesis of Mn(BQ)(DMSO)·DMSO (1), a potent metalloantibiotic with a dual antimicrobial mode of action against four different strains of (SA) bacteria (MIC = 0.625 μg mL). Additionally, 1 can overcome ciprofloxacin-resistance in methicillin-resistant SA bacteria.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/d3dt01904g | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Chargeable Hydrogels with Dual Modulatory Effects of Bacterial Killing and Immune Remodeling toward Wound Healing.
ACS Appl Mater Interfaces
September 2025
State Key Laboratory of Cardiovascular Diseases and Medical Innovation Center, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 200070, China.
Wound infections challenge clinical medicine, and developing novel therapies is critically important in overcoming antimicrobial resistance and an off-balanced immune microenvironment. Electrical stimulation as a biocompatible, easy-to-operate, and controllable technique has great potential in eradicating pathogens and modulating the immune system. However, safe and soft platforms that integrate both bactericidal and immunological modulatory effects of electrical stimulation are rarely reported.
View Article and Find Full Text PDFAlternating Magnetic Fields Remove Biofilms but Damage Cells on Implant Models Also with Negligible Bulk Heating.
ACS Appl Mater Interfaces
September 2025
Institute of Colloid and Biointerface Science, Institute of Colloid and Biointerface Science, BOKU University, 1190 Vienna, Austria.
Implant-associated infections caused by bacterial biofilms remain a major clinical challenge, with high morbidity, often necessitating prolonged antibiotic therapy or implant revision surgery. To address the need for noninvasive alternatives, we investigated the use of alternating magnetic fields (AMFs) as a localized treatment modality for eradicating biofilms on titanium implant model surfaces. We demonstrate that AMF exposure effectively removes biofilms and kills bacteria at moderately elevated temperatures on the implant.
View Article and Find Full Text PDFDual-signal colorimetric sensor based on Fe,Ce-CDs for ultra-sensitive detection of nitrite in tobacco.
Mikrochim Acta
September 2025
Faculty of Life Science and Technology, Kunming University of Science and Technology, Yunnan Province, 650500, China.
Iron-cerium co-doped carbon dots (Fe,Ce-CDs) were synthesized by one-step hydrothermal method using tartaric acid and L-tryptophan as ligands. Fe,Ce-CDs shows excellent peroxidase-like (POD) activity and nitrite (NO) can promote the oxidation of 3,3',5,5'-tetramethylbenzidine (TMB) to its blue oxidation product (oxTMB) due to the formation of ∙NO free radical. NO further react with oxTMB to form a yellow color via diazotization resulting in the absorbance Change at 450 nm.
View Article and Find Full Text PDFDevelopment and application of dialdehyde starch-grafted ε-polylysine copolymers as eco-friendly fruit detergents.
Food Chem
September 2025
Key Laboratory of Screening, Prevention, and Control of Food Safety Risks, State Administration for Market Regulation, Jiangnan University, Wuxi, Jiangsu Province, China; School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu Province, China; State Key Laboratory of Food Science a
Chemical detergents are extensively used to remove pesticide residues and foodborne pathogens on fresh fruits, but their residues are toxic to humans. To address this issue, a dual-functional starch copolymer, specifically dialdehyde starch-grafted ε-polylysine copolymer (DIA-ε-PL starch), was synthesized utilizing native starch with surfactant properties and the natural antimicrobial cationic peptide ε-polylysine (ε-PL). The effectiveness of DIA-ε-PL starch as a fruit detergent was subsequently evaluated.
View Article and Find Full Text PDFUnmasking Tacrolimus Toxicity due to the Hacked Liver System.
Ther Drug Monit
September 2025
Departments of Pharmacology, and.
Background: Fluconazole-tacrolimus interactions occur, but the additional effect of ritonavir is emphasized here, underscoring the need for careful prescription reconciliation in renal transplant recipients living with HIV-AIDS to prevent accidental ritonavir coadministration and inadvertent tacrolimus toxicity. The findings provide valuable insight for therapeutic drug monitoring (TDM) specialists. Patient informed consent was obtained for publication of the anonymized data.
View Article and Find Full Text PDF