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Opioid medications are commonly prescribed after pediatric orthopaedic surgery, but there is a critical need to optimize prescribing practice. This study identifies socio-economic characteristics, surgical characteristics, and patient reported psychological factors influencing postoperative opioid use in this population and found that post-operative opioid use in this pediatric orthopaedic population is multifactorial. Physicians should consider implementing protocols for initial opioid prescriptions to cover two to three days following common orthopaedic surgeries for most pediatric patients.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441272 | PMC |
Nat Aging
September 2025
Aging Biomarker Consortium (ABC), Beijing, China.
The global surge in the population of people 60 years and older, including that in China, challenges healthcare systems with rising age-related diseases. To address this demographic change, the Aging Biomarker Consortium (ABC) has launched the X-Age Project to develop a comprehensive aging evaluation system tailored to the Chinese population. Our goal is to identify robust biomarkers and construct composite aging clocks that capture biological age, defined as an individual's physiological and molecular state, across diverse Chinese cohorts.
View Article and Find Full Text PDFAnn Afr Med
September 2025
Department of Orthopaedics, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Introduction: Pediatric endotracheal intubation is challenging due to airway anatomical differences. Accurate endotracheal tube (ETT) sizing is crucial for effective ventilation and preventing complications. Traditional age, weight, or height-based methods are often unreliable, leading to multiple attempts.
View Article and Find Full Text PDFJ Am Acad Orthop Surg Glob Res Rev
September 2025
From the Harvard Medical School, Boston, MA (Gabriel, Hines, and Prabhat); the Lenox Hill Hospital, New York, NY (Dr. Ang); and the Boston Children's Hospital, Department of Orthopedic Surgery, Boston, MA (Dr. Liu and Dr. Hogue).
Purpose: The purpose of this study was to develop a comprehensive step-wise management algorithm for Bertolotti syndrome in the pediatric population by conducting a systematic review of the current literature regarding the diagnostic evaluation, nonsurgical and surgical treatment, and outcomes.
Methods: A systematic review of the literature was conducted using PubMed to identify studies focused on the management of Bertolotti syndrome in the pediatric population. Data extraction of clinical presentation, management strategies, imaging, and outcomes was completed.
Neurosurgery
September 2025
Department of Neurosurgery, John Radcliffe Hospital, Oxford, UK.
Background And Objectives: Chiari 1 malformation (CM1) is a common MRI finding and a frequent reason for neurosurgical consultation. Although many studies have investigated surgical outcomes for patients with CM1, outcomes for those treated without surgery have been less frequently reported. The UK Chiari 1 Study reports the quality of life of adults and children with CM1 treated without surgery, 12 months after the first neurosurgical clinic visit.
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