98%
921
2 minutes
20
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10426745 | PMC |
http://dx.doi.org/10.3389/fimmu.2023.1201989 | DOI Listing |
Nutrients
August 2025
CNR Institute of Neuroscience, 35127 Padova, Italy.
The present article is an opinion piece mainly based on selected articles in the field of sarcopenia, with possible relevance for pregnancy. Sarcopenia has gained increasing interest in recent years, since it has emerged that sarcopenia may determine significant health consequences, with related substantial health care expenditure. In particular, some studies suggested that sarcopenia may cause increased risk for several diseases, such as type 2 diabetes, obesity, and major cardiovascular events.
View Article and Find Full Text PDFInt J Mol Sci
August 2025
Department of Allergy, Immunology, Rheumatology, Division of Pediatrics, Stanford University School of Medicine, Palo Alto, CA 94305, USA.
Among the shared pathogenetic mechanisms leading to neurodevelopmental disorders (NDDs), a dysregulated inflammatory response has been described as a convergent pathway in NDDs. This scoping review was registered in the OSF database. It was conducted in accordance with the PRISMA Extension for Scoping Reviews, utilizing a comprehensive literature search of major academic databases, including PubMed and Web of Science.
View Article and Find Full Text PDFPLoS One
August 2025
Bioinformatics Lab (Dry), Department of Statistics, University of Rajshahi, Rajshahi, Bangladesh.
Introduction: Type 2 diabetes (T2D) is considered as a risk factor for kidney cancer (KC). However, so far, there is no study in the literature that has explored genetic factors through which T2D drive the development and progression of KC. Therefore, this study attempted to explore T2D- and KC-causing shared key genes (sKGs) for revealing shared pathogenesis and therapeutic drugs as their common treatments.
View Article and Find Full Text PDFmedRxiv
August 2025
New England Eye Center, Tufts Medical Center, Boston, MA, USA.
Adverse drug reactions are a frequent cause of worldwide morbidity and mortality. Glucocorticoids (GCs), commonly used to treat inflammatory diseases, alter gene expression with both beneficial and adverse consequences. When used in the eye, GCs cause steroid-induced ocular hypertension (SIOH) in 30-50% of patients, leading to steroid-induced glaucoma.
View Article and Find Full Text PDFNeurosci Lett
August 2025
MMDN, Univ Montpellier, EPHE, INSERM, Montpellier, France. Electronic address:
Alzheimer's disease (AD) is the most common dementia, with rising global prevalence, still incomplete pathogenetic understanding and very limited effective therapies. Recent advances in biomarker identification of Aβ peptides and phospho-tau protein, and in anti-Aβ immunotherapy are suggesting that more early intervention will be more effective. Alternative therapeutic strategies to anti-Aß immunotherapy have received comparably less attention, yet one specific approach toward upstream neuroprotection by improvement of intracellular calcium homeostasis, activation of endogenous neuroprotection and restoration of autophagy through sigma-1 receptor activation recently demonstrated positive clinical data with oral blarcamesine in a phase IIb/III trial in 508 patients with early AD.
View Article and Find Full Text PDF