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Background: Glenohumeral joint instability and dislocation are common orthopedic pathologies that can produce osseous humeral head defects such as Hill-Sachs (HS) or Reverse Hill-Sachs (RHS) lesions. Numerous reconstruction techniques have been reported in the literature, including remplissage, disimpaction, and allograft reconstruction. No group has previously assessed the outcomes of allograft reconstruction for RHS lesions, nor compared the outcomes of allograft reconstruction for HS and RHS lesions. In this study, we aim to provide a comprehensive assessment of osteochondral allograft reconstruction for the distinct pathologies of RHS lesions and HS lesions by comparing postreconstruction patient-reported outcomes, complications, and radiographic assessments for each lesion.
Methods: Using Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines, a systematic review was performed to identify and include studies that reported patient outcomes after the use of osteochondral allografts in the reconstruction of HS or RHS lesions of the humeral head. A comprehensive search of the Google Scholar, PubMed, and Embase databases was conducted with the key terms "allograft," "Hill-Sachs," and "reverse Hill-Sachs."
Results: Eight studies, with a total of 84 patients, were included for review. Of the 84 allograft-treated patients, there were 44 patients with HS lesions and 40 patients with RHS lesions. The average patient age was 27.3 years for HS lesions and 43.0 years for RHS lesions. Postoperative range of motion and average Constant-Murley score (87.9 for HS and 80.1 for RHS) appeared to be greater for those with HS lesions. In addition, 20.5% of HS patients experienced postoperative complications, whereas 42.5% of RHS patients had postoperative complications ( = .03). HS and RHS patients experienced similar proportions of graft resorption or collapse rate (22.7% for HS and 12.5% for RHS; = .2).
Conclusion: Patient-reported outcomes indicate that osteochondral allograft reconstruction for large RHS and HS lesions is an acceptable intervention. RHS patients had lower rates of graft resorption and collapse but worse postoperative range of motion and functional outcomes, although these differences were not statistically significant. HS patients experienced significantly fewer complications than those with RHS lesions.
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http://dx.doi.org/10.1016/j.xrrt.2022.07.001 | DOI Listing |
Can J Ophthalmol
September 2025
University of British Columbia, Department of Ophthalmology and Visual Sciences, Vancouver, BC, Canada.
Objective: To assess the effect of belzutifan, a first-in-class oral hypoxia-inducible factor 2α inhibitor, on retinal hemangioblastoma (RH) outcomes.
Subjects/methods: This is a single-centre retrospective cohort study of patients with confirmed von Hippel-Lindau syndrome (VHLS) and RH. Subjects were taking oral belzutifan for renal cell carcinoma, central nervous system hemangioblastoma, or pancreatic neuroendocrine tumours.
Brain Sci
July 2025
Department of Neurology, Johns Hopkins School of Medicine, 600 N Wolfe Street, Baltimore, MD 21287, USA.
: Successful discourse relies not only on linguistic but also on prosodic information. Difficulty recognizing emotion conveyed through prosody (receptive affective aprosodia) following right hemisphere stroke (RHS) significantly disrupts communication participation and personal relationships. Growing evidence suggests that damage to white matter in addition to gray matter structures impairs affective prosody recognition.
View Article and Find Full Text PDFIEEE J Biomed Health Inform
April 2025
Despite the progress made in Mamba-based medical image segmentation models, existing methods utilizing unidirectional or multi-directional feature scanning mechanisms struggle to effectively capture dependencies between neighboring positions, limiting the discriminant representation learning of local features. These local features are crucial for medical image segmentation as they provide critical structural information about lesions and organs. To address this limitation, we propose SliceMamba, a simple yet effective locally sensitive Mamba-based medical image segmentation model.
View Article and Find Full Text PDFFront Neurosci
April 2025
Department of Pain Medicine, Affiliated Hospital of Guilin Medical University, Guilin, China.
Objective: Typical Ramsay Hunt syndrome (RHS) is a rare peripheral facial neuropathy associated with reactivation of latent varicella-zoster virus in the geniculate ganglion. Atypical RHS is characterized by the involvement of multiple cranial nerves and cervical roots, leading to more complex manifestations. The primary goal of treatment is to reduce the occurrence of late complications, especially in patients with devastating postherpetic neuralgia (PHN).
View Article and Find Full Text PDFRamsay Hunt syndrome (RHS) is a rare complication of varicella-zoster virus (VZV) reactivation, typically presenting with a combination of painful vesicular lesions in the ear, facial nerve palsy, and hearing loss. Early diagnosis and antiviral therapy are critical in minimizing long-term sequelae, such as persistent facial weakness and hearing impairment. This case highlights the importance of prompt recognition and treatment in older patients, particularly those with pre-existing hearing difficulties.
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