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http://dx.doi.org/10.1016/j.athoracsur.2023.08.001 | DOI Listing |
J Nurs Manag
September 2025
Division of Health Science, Graduate School of Medicine, The University of Osaka, 1-7 Yamadaoka, Suita, Osaka 565-0871, Japan.
In many developed countries, a rapidly aging population has increased healthcare demands and the proportion of older nurses in the workforce. This demographic shift requires nursing managers to have a deeper understanding of the physical demands on staff nurses, particularly older ones. In this paper, we aim to provide valuable insights for developing evidence-based strategies to improve work environments in hospital wards.
View Article and Find Full Text PDFJ Chromatogr A
August 2025
Waters Corporation, Core Research/Fundamental Milford, MA, 01757, USA.
Slalom chromatography (SC) has recently been revitalized through the latest available UHPLC columns and systems, alongside advances in better understanding its separation and mass transfer mechanisms. These developments have demonstrated its potential in the analysis of cell and gene therapy drug substances, including plasmid topology analysis, DNA restriction mapping, dsRNA impurity detection in IVT mRNA, and CRISPR-Cas9 ribonucleoprotein assays. However, SC's quantitative superiority over traditional agarose gel electrophoresis (AGE) remains unproven, and no accurate and predictive model has yet been reported for any commercial SC column for a wide range of experimental conditions of temperature, flow rate, and buffer concentration.
View Article and Find Full Text PDFBreast
August 2025
Palliative Care, Pain Therapy and Rehabilitation Unit, Fondazione IRCCS-Istituto Nazionale dei Tumori, Milan, Italy. Electronic address:
Background: Based on available data in the literature, current evidence supporting the analgesic role of antiresorptive drugs is weak. This study compared the efficacy of zoledronic acid (ZA) and denosumab (Dmab) in reducing bone pain and first Skeletal Related Events (SREs) in real world setting.
Methods: A retrospective observational cohort study was conducted in patients with female breast cancer-related bone metastases at the Fondazione IRCCS Istituto Nazionale dei Tumori in Milan, Italy, from January 2008 to January 2023.
Front Physiol
August 2025
Keizo Asami Institute, Federal University of Pernambuco, Recife, Pernambuco, Brazil.
Introduction: The Environmental Enrichment (EE) promotes systemic responses through social, cognitive, sensory, and physical stimuli. However, its effects on hepatic and muscle oxidative balance, as well as on serum inflammation markers, remain unclear. Therefore, this study aimed to evaluate whether three weeks of EE could modulate hepatic and muscular oxidative balance and the inflammatory response in female C57BL/6 mice.
View Article and Find Full Text PDFIndian J Plast Surg
August 2025
Department of Plastic Surgery,Universidad de Antioquia, Medellín, Colombia.
Background: Complex nasal reconstructions traditionally use staged flaps, with skin grafts reserved for smaller defects.
Objective: This study evaluates single-stage full-thickness skin grafting (FTSG) for wide nasal defects postcancer resection.
Materials And Methods: A retrospective analysis included 52 patients with nasal malignant lesions limited to the skin, reconstructed in a single stage immediately after cancer resections.