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The retention of Canada's advanced practice nurses (APNs), including clinical nurse specialists and nurse practitioners, is a national health human resources issue. APNs are essential within the Canadian healthcare workforce for meeting patient and population health needs, often in underserved communities. A shortage of APNs will exacerbate barriers to access to care for patients across sectors, including primary, acute, long-term and transitional care settings. This paper provides highlights from literature reporting on the state of APN human resources in Canada, including influential barriers and facilitators, and recommendations for retaining these important leaders in the healthcare workforce.
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http://dx.doi.org/10.12927/cjnl.2023.27126 | DOI Listing |
JMIR Hum Factors
September 2025
Seidenberg School of Computer Science and Information Systems, Pace University, New York City, NY, United States.
Background: As information and communication technologies and artificial intelligence (AI) become deeply integrated into daily life, the focus on users' digital well-being has grown across academic and industrial fields. However, fragmented perspectives and approaches to digital well-being in AI-powered systems hinder a holistic understanding, leaving researchers and practitioners struggling to design truly human-centered AI systems.
Objective: This paper aims to address the fragmentation by synthesizing diverse perspectives and approaches to digital well-being through a systematic literature review.
Dev World Bioeth
September 2025
Faculty of Law, University of Alberta, Edmonton, Alberta, Canada.
This article explores two complementary strategies for addressing the affordability and access challenges facing advanced therapies. As high development costs and limited market access have led to the withdrawal of several therapies, the article examines how these barriers create 'valleys of death' that prevent innovation from reaching patients. Through the case of Glybera and other examples, it outlines a rehabilitative approach focused on reforming current systems through improved reimbursement schemes, regulatory streamlining, and more efficient manufacturing.
View Article and Find Full Text PDFInflamm Res
September 2025
Department of Cardiology, Huashan Hospital, Fudan University, Shanghai, 200040, China.
Cardiovascular diseases (CVDs) are a group of conditions that significantly affect human health and are among the leading causes of death and disability worldwide. Clinical trials and basic research have demonstrated that inflammation plays a pivotal role in the development of CVDs. The inflammasome is a critical component of the innate immune system, involved in various inflammatory responses to pathogens and tissue damage.
View Article and Find Full Text PDFOsteoporos Int
September 2025
Department of Rheumatology, First Faculty of Medicine, Charles University, Katerinska 32, Prague, 121 08, Czech Republic.
Unlabelled: REMS-BMD by radiofrequency echographic multispectrometry is primarily determined by a patient's BMI, age, and sex. Only about 2.8% of the changes in femoral neck REMS-BMD can be attributed to replacement of the total hip with metal implants.
View Article and Find Full Text PDFJ Am Geriatr Soc
September 2025
Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, Florida, USA.