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http://dx.doi.org/10.1371/journal.ppat.1011521 | DOI Listing |
Nat Protoc
September 2025
Department of Plant-Microbe Interactions, Max Planck Institute for Plant Breeding Research, Cologne, Germany.
Structural biology is fundamental to understanding the molecular basis of biological processes. While machine learning-based protein structure prediction has advanced considerably, experimentally determined structures remain indispensable for guiding structure-function analyses and for improving predictive modeling. However, experimental studies of protein complexes continue to pose challenges, particularly due to the necessity of high protein concentrations and purity for downstream analyses such as cryogenic electron microscopy.
View Article and Find Full Text PDFPlant Sci
September 2025
Fermentation and Phytofarming Technology Division, CSIR-Institute of Himalayan Bioresource Technology, Palampur-176061, Himachal Pradesh, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad-201002, India. Electronic address:
Auxin, one of the earliest recognized and extensively investigated phytohormones, is crucial in plant growth and survival in adverse environmental conditions. Two gene families primarily regulate auxin signaling: auxin response factors (ARFs) and auxin/indole-3-acetic acid (Aux/IAA). Aux/IAA family proteins are recognized as essential elements of the nuclear auxin signaling system, inhibiting gene transcription in their presence and facilitating gene activation upon their degradation.
View Article and Find Full Text PDFDtsch Med Wochenschr
September 2025
LMU Klinikum, Ludwig-Maximilians-Universität (LMU) München, Institut und Poliklinik für Arbeits-, Sozial- und Umweltmedizin, Comprehensive Allergy Center München (CAC-M), München, Deutschland.
The COVID-19 pandemic led to a sharp increase in the recognitions of COVID-19 as an occupational disease in Germany. The patients often report diverse symptoms, whereas causality and objectification remain difficult.A selective literature research in PubMed was carried out, assessment recommendations and guidelines were included, too.
View Article and Find Full Text PDFMicrob Genom
September 2025
Department of Infectious Diseases and Public Health, Jockey Club College of Veterinary Medicine and Life Sciences, City University of Hong Kong, Hong Kong, PR China.
African swine fever virus (ASFV) is highly transmissible and can cause up to 100% mortality in pigs. The virus has spread across most regions of Asia and Europe, resulting in the deaths of millions of pigs. A deep understanding of the genetic diversity and evolutionary dynamics of ASFV is necessary to effectively manage outbreaks.
View Article and Find Full Text PDFJ Robot Surg
September 2025
Department of Research and Innovation, Medway NHS Foundation Trust, Gillingham, ME7 5NY, UK.
Robotic surgery has transformed the field of surgery, offering enhanced precision, minimal invasiveness, and improved patient outcomes. This narrative review explores the multifaceted aspects of robotic surgery, examining the challenges, recent advances, and future prospects for its integration into healthcare. Our comprehensive analysis of 48 studies reveals significant geographic disparities in robotic surgery research and implementation, with 68.
View Article and Find Full Text PDF