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http://dx.doi.org/10.1093/ofid/ofad323 | DOI Listing |
Int J Surg
September 2025
Department of Anesthesiology, Qingdao Municipal Hospital, Qingdao, Shandong Province, China.
Background: As a common postoperative neurological complication, postoperative delirium (POD) can lead to poor postoperative recovery in patients, prolonged hospitalization, and even increased mortality. However, POD's mechanism remains undefined and there are no reliable molecular markers of POD to date. The present work examined the associations of cerebrospinal fluid (CSF) sTREM2 with CSF POD biomarkers, and investigated whether the effects of CSF sTREM2 on POD were modulated by the core pathological indexes of POD (Aβ42, tau, and ptau).
View Article and Find Full Text PDFComput Methods Biomech Biomed Engin
September 2025
Center for Medical Metrology, National institute of metrology, Beijing, China.
Geometric changes in the sigmoid sinus diverticulum (SSD) can alter its hemodynamic - a primary factor contributing to pulsatile tinnitus (PT). However, not all SSD cases lead to clinical PT symptoms. This study aims to investigate the influence of the diameter of the diverticulum (EDD) on the hemodynamics of the sigmoid sinus in PT.
View Article and Find Full Text PDFCochrane Database Syst Rev
September 2025
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
Background: Radiotherapy is the mainstay of treatment for head and neck cancer (HNC) but may induce various side effects on surrounding normal tissues. To reach an optimal balance between tumour control and toxicity prevention, normal tissue complication probability (NTCP) models have been reported to predict the risk of radiation-induced side effects in patients with HNC. However, the quality of study design, conduct, and analysis (i.
View Article and Find Full Text PDFCancer Manag Res
September 2025
Department of Pain, The First People's Hospital of Zunyi City, Zunyi, Guizhou, 563000, People's Republic of China.
Objective: To evaluate the effects of a comprehensive intervention program on cancer pain and self-efficacy in patients with lung cancer.
Methods: A total of 120 lung cancer patients with cancer pain who received treatment from January 2021 to December 2023 at The First People's Hospital of Zunyi were enrolled in this study. A within-subject design was used, comparing patients' pain and self-efficacy scores before and after a comprehensive intervention.
JGH Open
September 2025
Department of Genomic Medicine, Division of Biochemistry, Molecular Biology, and Nutrition University Hospital of Nancy Nancy France.
Introduction: Cirrhosis progresses from compensated to decompensated phases, often marked by portal hypertension and complications like ascites, variceal hemorrhage, and hepatic encephalopathy. The ammonia-to-urea (A-to-U) ratio, reflecting urea cycle efficiency, may offer superior diagnostic performance compared to plasma ammonia levels alone. This study compared the diagnostic accuracy of the A-to-U ratio and plasma ammonia levels for identifying portal hypertension.
View Article and Find Full Text PDF