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Purpose: To assess the characteristics of completed panretinal photocoagulation (PRP), using ultra-widefield imaging in proliferative diabetic retinopathy.
Methods: Quantitative assessment of ultra-widefield imaging images of 133 patients with proliferative diabetic retinopathy with completed PRP was made using ImageJ software. The parameters assessed included distance of laser spots from the optic disk, foveal center, superior and inferior arcades, and extent of the maximum width of laser. Areas assessed were total area of the image, area of the inner limit within which laser spots are restricted, minimum areas of unlasered patches, total area lasered, and ideal area to be covered by PRP.
Results: Two hundred one images were assessed for the final analysis. The mean distance of laser spots was 4.2 ± 2.4 mm from the optic disk (nasal) and 6.6 ± 2.5 mm from the foveal center (temporal). The mean distance of laser spots from the superior arcade vessel was 3.2 ± 1.9 mm and 6.2 ± 4.4 mm from the inferior arcade. The mean area of the retina that should have been ideally lasered was found to be 900 ± 267 mm 2 , and the actual area lasered was found to be 681 ± 254.4 mm 2 .
Conclusion: Approximately one-quarter area of the retina continues to remain ischemic because of the lack of inadequate coverage of PRP. Further longitudinal studies are recommended, using ultra-widefield imaging to objectively assess the adequacy of PRP and its role in modulating the course of progression of the retinopathy.
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http://dx.doi.org/10.1097/IAE.0000000000003902 | DOI Listing |
Ophthalmol Sci
July 2025
Department of Ophthalmology, Shinshu University School of Medicine, Matsumoto, Nagano, Japan.
Purpose: This study evaluates retinal volume in the macula and peripheral retina in patients with nonproliferative diabetic retinopathy (NPDR), with and without diabetic macular edema (DME), using widefield swept-source OCT (SS-OCT).
Design: Retrospective observational study.
Participants: A total of 98 eyes were included: 30 from patients with NPDR without DME (DME-), 38 from patients with NPDR with DME (DME+), and 30 from age- and sex-matched healthy controls.
BMC Ophthalmol
August 2025
Department of Ophthalmology, Peking University First Hospital, Beijing, China.
Background: Sturge-Weber syndrome (SWS) is a rare congenital phacomatosis disorder. choroidal hemangioma (CH) is one of the most common ocular manifestations. The advancements in swept-source optical coherence tomography angiography (SS-OCTA) provide us a comprehensive view of the CH.
View Article and Find Full Text PDFObjectives: This study aims to detect characteristic fundus changes in pathological myopia using deep learning (DL)-based analysis of ultra-widefield (UWF) fundus imaging.
Methods: Following the exclusion of low-quality images, this cross-sectional study used 1105 UWF images from 543 patients with high myopia to develop the model, along with 293 images from 150 patients with high myopia for external testing. All images were retrospectively collected from patients with high myopia at Shanghai General Hospital and Shanghai Eye Diseases Prevention and Treatment Center between 2018 and 2024.
Surv Ophthalmol
August 2025
University of Pittsburgh School of Medicine, Department of Medical Retina and Vitreoretinal Surgery, 203 Lothrop Street, Suite 800, Pittsburg, PA 15213.
The term pachychoroid, derived from the Greek word pachy meaning "thick," refers to a choroidal phenotype characterized by increased choroidal thickness, dilated outer choroidal vessels (pachyvessels), and attenuation of the overlying Sattler layer and choriocapillaris. Initially recognized in central serous chorioretinopathy, this phenotype is now acknowledged as the underlying pathophysiological basis for a broader spectrum of retinal disorders, including pachychoroid pigment epitheliopathy, pachychoroid neovasculopathy, polypoidal choroidal vasculopathy, focal choroidal excavation, peripapillary pachychoroid syndrome, pachydrusen and pachychoroid geographic atrophy. Collectively referred to as the pachychoroid disease spectrum, these entities share common features such as structural choroidal remodeling, choroidal vascular hyperpermeability, and outer retinal or retinal pigment epithelial changes.
View Article and Find Full Text PDFOphthalmol Retina
August 2025
Harvard Retinal Imaging Lab, Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA; Retina Service, Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA. Electronic address:
Purpose: To assess the severity and clinical significance of intraretinal microvascular abnormalities (IRMA) using expanded field swept-source OCT Angiography (SS-OCTA) in eyes with non-proliferative diabetic retinopathy (NPDR).
Design: Cross-sectional, observational study.
Participants: 139 eyes from 101 subjects with NPDR.