Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Neoplasms that cause tumor-induced osteomalacia are very rarely located in the lung. A 27-year-old man underwent a surgery in the right femoral head to remove the tumor that induced osteomalacia 8 years ago with complete symptomatic relief. However, his bone pain occurred again recently, which lead to suspicion of a recurrent tumor-induced osteomalacia. 68 Ga-DOTATATE PET/CT images showed a pulmonary nodule with mildly increased uptake along with increased activity in the left foot. The pulmonary nodule was subsequently resected and was pathologically confirmed as a phosphaturic mesenchymal tumor. The symptoms were completely relieved postsurgery.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/RLU.0000000000004771 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Clinical Characteristics and Management of Rare Metabolic Bone Diseases: An Audit of the Rare Metabolic Bone Disease Registry of India.
Calcif Tissue Int
September 2025
Department of Endocrinology, Post-Graduate Institute of Medical Education and Research (PGIMER), 001, Nehru Extension Block, Chandigarh, India.
Rare diseases, defined by the 2002 Rare Disease Act, affect fewer than 5 in 10,000 individuals. Rare metabolic bone diseases (MBDs), such as osteogenesis imperfecta, hypophosphatasia, osteopetrosis, and other unclassified disorders, can disrupt bone development and remodeling, posing diagnostic and management challenges. This study analyzed data from the rarembd.
View Article and Find Full Text PDFA Sinonasal Paranasal Mesenchymal Tumor Associated With Tumor-Induced Osteomalacia: A Case Report and Literature Review.
Ear Nose Throat J
September 2025
International Medical Center Ward, General Practice Medical Center, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China.
Introduction: Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome that is characterized by hypophosphatemia resulting from the leakage of renal phosphate. Due to its diverse and nonspecific clinical manifestations, the diagnosis is often delayed.
Case Report: We present the rare case of a 33-year-old man with TIO who was presented with chronic bilateral hip joint pain and was initially misdiagnosed with osteonecrosis of the femoral head.
Diagnostic Journey in the Recognition of Oncogenic Osteomalacia.
JCEM Case Rep
October 2025
Department of Neurological Surgery, Sidney Kimmel College of Medicine, Thomas Jefferson University, Philadelphia, PA.
A 73-year-old woman with a remote history of successfully treated primary hyperparathyroidism was referred to our office because of multiple skeletal fractures and proximal muscle weakness. Prior laboratory evaluation demonstrated hypocalcemia, vitamin D deficiency, elevated PTH, and elevated alkaline phosphatase. Updated evaluation in our clinic additionally showed hypophosphatemia prompting measurement of serum fibroblast growth factor 23 (FGF23).
View Article and Find Full Text PDFFailure of femoral internal fixation device secondary to phosphaturic mesenchymal tumor: a case report and literature review.
BMC Musculoskelet Disord
September 2025
The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Background: Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome caused by mesenchymal tumors that secrete fibroblast growth factor 23 (FGF23). Phosphaturic mesenchymal tumor (PMT) is a novel histopathologic entity that has been identified as a separate cause of TIO. Clinically, PMT is typically diagnosed late due to its rarity.
View Article and Find Full Text PDFPET/CT and Paraneoplastic Syndromes: A Comprehensive Review.
Cancers (Basel)
August 2025
Department of Radiology, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.
Paraneoplastic syndromes (PNSs) are pathologic conditions produced by neoplasms not attributable to tumor invasion or metastasis. The clinical manifestations of PNSs can precede the diagnosis; these symptoms may serve as early indicators of underlying malignancy. Standard imaging modalities, such as computed tomography (CT) and magnetic resonance imaging (MRI), have limited sensitivity in detecting small or early-stage PNS-associated tumors.
View Article and Find Full Text PDF