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http://dx.doi.org/10.1111/den.14625 | DOI Listing |
Arq Bras Cardiol
September 2025
Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP - Brasil.
Targeted temperature management (TTM) is currently the only potentially neuroprotective intervention recommended for post-cardiac arrest care. However, there are concerns among the scientific community regarding conflicting evidence supporting this recommendation. Moreover, the bulk of trials included in systematic reviews that inform guidelines and recommendations have been conducted in developed countries, with case mix and patient characteristics that significantly differ from the reality of developing countries such as Brazil.
View Article and Find Full Text PDFNeuropsychiatr Dis Treat
August 2025
Department of Psychiatry and Behavioral Sciences, New York Medical College, Valhalla, New York, USA.
Brexpiprazole is a second-generation antipsychotic with multiple indications, including the treatment of schizophrenia. As a partial dopamine agonist, brexpiprazole differs from most other antipsychotics, yet uncertainties about its full mechanism of action have led to some ambiguity among prescribers. To address this gap, an international panel of psychiatric experts was organized and convened with funding from Otsuka Pharmaceutical Europe Ltd and H.
View Article and Find Full Text PDFRadiographics
October 2025
Division of Neuroradiology, Department of Diagnostic and Interventional Radiology, The Hospital for Sick Children, Toronto, Ontario, Canada.
Pediatric stroke is garnering increased attention due to its rising incidence and significant impact on affected children, families, and the health care system. Arterial ischemic stroke (AIS) is a major subtype of pediatric stroke and often results from arterial occlusion. Diagnosis and treatment of acute ischemic stroke in children pose unique challenges, primarily because of nonspecific symptoms, lack of pediatric-focused imaging protocols, distinct causes (compared with in adults), and the large number of stroke mimics.
View Article and Find Full Text PDFJ Perianesth Nurs
September 2025
Department of Anesthesiology, The Second Affiliated Hospital of Xiamen Medical College, Xiamen, Fujian, China. Electronic address:
Purpose: This study aimed to evaluate the effects of different doses of esketamine with etomidate on anesthesia and postoperative cognitive function of elderly patients undergoing painless tracheoscopy.
Design: This was a double-blind, randomized controlled trial.
Methods: In this study, 150 patients over 65 were divided into group A (low-dose: 0.
Endoscopy
September 2025
Centre for Biomaterials and Tissue Engineering, Universitat Politècnica de València, Valencia, Spain.
Objectives: We aimed to perform a multifactorial carbon footprint assessment and sensitivity analysis of the colonoscopy procedure.
Design: One-week single-center prospective study with all outpatients' diagnostic colonoscopies was realized (n=66). A cradle-to-grave life cycle assessment (LCA) methodology evaluated all essential supplies (accessories from 1 to 15), endoscopic procedure (energy consumption, CO2 insufflation, bowel preparation, and sedation), staff and patients transport and waste management.