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Herein, we present a Zn(II)-catalyzed (3 + 3) heteroannulation reaction between aromatic amines and 1,3-diynamides for the synthesis of amidoquinolines. A large number of aromatic amines are well tolerated, furnishing quinoline derivatives in up to excellent yield. Notably, various reactive functional groups have survived under the optimal reaction conditions, highlighting the mildness of the developed protocol. In addition, amines derived from bioactive molecules show modest reactivity.
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http://dx.doi.org/10.1021/acs.joc.3c00568 | DOI Listing |
Dalton Trans
September 2025
Department of Chemistry, Jadavpur University, Kolkata - 700032, India.
An interesting ruthenium(III) complex, -[Ru(HL)Cl(PPh)], has been synthesized using a redox-active tetradentate bis-azo diamine ligand (HL). This complex represents the first example of a structurally robust, air- and moisture-stable coordination compound featuring a redox non-innocent ligand that provides a unique N4 donor set comprising both strong π-acidic (azo) and σ-donating (amido) groups. The complex has been comprehensively characterized by elemental analysis, various spectroscopic techniques, and single-crystal X-ray diffraction (SCXRD) studies.
View Article and Find Full Text PDFOrg Lett
September 2025
Department of Chemistry, Virginia Tech, Blacksburg, Virginia 24061, United States.
, a lactic acid gut bacterium, uses exogenous quinones to facilitate extracellular electron transfer (EET) via type II NADH dehydrogenase (Ndh2). To probe Ndh2 specificity, we designed and evaluated a library of biogenic amine-substituted 1,4-naphthoquinones in an Ndh2-dependent EET assay. Analysis of mediator Ndh2 binding interactions revealed that activity correlates with key binding interactions.
View Article and Find Full Text PDFSmall Methods
September 2025
Department of Chemistry, National Central University, Jhong-Li, 32001, Taiwan (ROC).
A new, readily accessible inorganic hole transporting material (HTM), Cu doped SnCoO (Cu-SCO), is developed for inverted tin-perovskite solar modules (TPSMs). To overcome the intrinsic defect of inorganic solid-state material Cu-SCO and potential interfacial incompatibility with TPsk, an amphiphilic neutral donor-acceptor copolymer (PTSN) is rationally designed as a surface/interface modification agent. TPSMs based on Cu doped SnCoO HTLs integrated with PTSN surface/interface modification achieved the highest conversion efficiency of 10.
View Article and Find Full Text PDFAnal Chem
September 2025
Department of Chemistry, Capital Normal University, Beijing 100048, China.
Single-atom nanozymes have made important progress in the field of sensors, but their catalytic performance as natural enzyme substitutes is far from satisfactory. We describe here a FeFe dual single-atom nanozyme (FeNCN) with a Fe loading of 0.89 wt %, and it shows a synergistic effect and a peroxidase (POD)-like activity.
View Article and Find Full Text PDFChem Sci
August 2025
Guangdong Basic Research Center of Excellence for Aggregate Science, School of Science and Engineering, The Chinese University of Hong Kong, Shenzhen (CUHK-Shenzhen) Guangdong 518172 China.
The p-π conjugated polymers have garnered considerable interest owing to their distinctive electronic structures, which arise from the interaction between p orbitals and π electrons. Currently, the p-π conjugated polymers with charged side chains have been extensively studied, those featuring charged backbones are rare due to the synthetic difficulties. In this work, we developed a spontaneous amino-yne click polymerization utilizing pyridinium-activated alkyne and aromatic primary amine monomers, enabling the efficient synthesis of p-π conjugated ionic polymers with high weight-average molecular weights ( , up to 44 100) and excellent yields (up to 98%).
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