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Liaoning cashmere goat (LCG) is one of the excellent cashmere goat breeds in China. Because of its larger size, better cashmere, and better cashmere production performance, people pay special attention to it. This article mainly studied the relationship between SNP loci of gene and gene and milk production, cashmere production and body measurement traits of LCGs. We further identified potential SNP loci by PCR-Seq polymorphism detection and gene sequence comparison of and genes. Further, we use SPSS and SHEsis software to analyze their relationship to production performance. The consequence indicated that CC genotype of gene T16409C locus was dominant genotype in milk production and cashmere production, while CT genotype of gene T16409C locus was dominant in body size. The CT genotype of C168T locus of gene is the dominant genotype of body type and cashmere production, while the dominant genotype of milk production is TT genotype. Through joint analysis, in haploid combinations, H1H2:CCCT is the dominant haplotype combination in cashmere fineness. H3H4:TTCT is a dominant haplotype combination of milk production traits and body measurement traits. These dominant genotypes can provide a reliable basis for the study of production performance of LCG.
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http://dx.doi.org/10.1080/10495398.2023.2230484 | DOI Listing |
Stress Biol
September 2025
Shaanxi Key Laboratory of Molecular Biology for Agriculture, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, China.
Understanding the genetic mechanism of cold adaptation in cashmere goats and dairy goats is very important to improve their production performance. The purpose of this study was to comprehensively analyze the genetic basis of goat adaptation to cold environments, clarify the impact of environmental factors on genome diversity, and lay the foundation for breeding goat breeds to adapt to climate change. A total of 240 dairy goats were subjected to genome resequencing, and the whole genome sequencing data of 57 individuals from 6 published breeds were incorporated.
View Article and Find Full Text PDFBMC Res Notes
August 2025
Department of Animal Science, Fars Agricultural and Natural Resources Research and Education Center, Agricultural Research, Education & Extension Organization (AREEO), Fars, Iran.
Objective: The Raeini Cashmere goat, native to Kerman Province, Iran, is renowned for its high-quality cashmere fiber, a luxury natural fiber valued for its softness, warmth, and lightweight properties in the textile industry. This breed, adapted to the region's arid climate through long-term natural and artificial selection, supports the local agricultural economy through cashmere, meat, and milk production. This study presents the first whole-genome resequencing dataset for the Raeini Cashmere goat, providing a valuable resource for ecological, evolutionary, and population genomic studies.
View Article and Find Full Text PDFFront Vet Sci
July 2025
Institute of Animal Nutrition and Feed, Academy of Agriculture and Animal Husbandry Sciences, Hohhot, China.
Hair follicle development and cycling are governed by intricate genetic and molecular networks, with microRNAs (miRNAs) playing essential roles as post-transcriptional regulators. In cashmere goats, valued for their fine fiber, miRNAs have emerged as key modulators influencing hair follicle morphogenesis, regeneration, and fiber traits such as fineness and pigmentation. This review highlights recent discoveries in miRNA-mediated regulation of hair follicles, focusing on their dynamic expression patterns and cell-specific functions in keratinocytes, dermal papilla cells, and follicular stem cells.
View Article and Find Full Text PDFInt J Biol Macromol
August 2025
Sanya Research Institute of Nanjing Agricultural University, Nanjing Agricultural University, Sanya 572000, China. Electronic address:
Skeletal muscle development directly impacts meat quality and productivity in livestock. Although N6-methyladenosine (m6A) RNA methylation has been recognized as a crucial epigenetic mechanism governing myogenesis, the specific functions of Insulin-like Growth Factor 2 mRNA-binding Protein 3 (IGF2BP3), a key m6A reader protein, in goat muscle development remain elusive. This study was designed to dissect the role of IGF2BP3 and its m6A-mediated regulatory mechanisms during goat skeletal muscle development.
View Article and Find Full Text PDFObjective: Inner Mongolia cashmere goats are superior indigenous breeds developed through long-term natural selection and systematic artificial selection, which have experienced a certain intensity of selection pressure during the breeding process, leading to bipolar differentiation trends in cashmere traits. Therefore, identifying genomic selection signatures associated with cashmere traits in Inner Mongolia cashmere goats is crucial for breeding high-quality cashmere-producing goats.
Methods: To unravel the genetic basis of cashmere traits, this study stratified 375 Inner Mongolia cashmere goats into eight subgroups based on breeding values for cashmere traits: high-yield vs low-yield cashmere types (HYCG vs LYCG), fine vs coarse cashmere types (FCG vs CCG), long vs short cashmere types (LCG vs SCG), and long vs short fleece types (LFCG vs SFCG).