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Disturbed interoception (i.e., the sensing, awareness, and regulation of internal body signals) has been found across several mental disorders, leading to the development of interoception-based interventions (IBIs). Searching PubMed and PsycINFO, we conducted the first systematic review of randomized-controlled trials (RCTs) investigating the efficacy of behavioral IBIs at improving interoception and target symptoms of mental disorders in comparison to a non-interoception-based control condition [CRD42021297993]. Thirty-one RCTs fulfilled inclusion criteria. Across all studies, a pattern emerged with 20 (64.5%) RCTs demonstrating IBIs to be more efficacious at improving interoception compared to control conditions. The most promising results were found for post-traumatic stress disorder, irritable bowel syndrome, fibromyalgia and substance use disorders. Regarding symptom improvement, the evidence was inconclusive. The IBIs were heterogenous in their approach to improving interoception. The quality of RCTs was moderate to good. In conclusion, IBIs are potentially efficacious at improving interoception for some mental disorders. In terms of symptom reduction, the evidence is less promising. Future research on the efficacy of IBIs is needed.
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http://dx.doi.org/10.1111/pcn.13576 | DOI Listing |
JMIR Res Protoc
September 2025
Division of Physical Therapy and Rehabilitation Science, Department of Family Medicine and Community Health, Medical School, University of Minnesota-Twin Cities, Minneapolis, MN, United States.
Background: Approximately 69% of Americans with spinal cord injury (SCI) have neuropathic pain. Research suggests that impairments in mental body representations (MBRs; ie, representations of the body in the brain) likely contribute to neuropathic pain. Clinical trials in adults with SCI, focused on restoring MBR, led to improvements in sensation and movement as well as neuropathic pain relief.
View Article and Find Full Text PDFBMJ Open
September 2025
Department of Consultation-Liaison Psychiatry and Psychosomatic Medicine, University Hospital Zurich, University of Zurich, Zurich, Switzerland
Introduction: Coronary artery bypass grafting (CABG) remains one of the most commonly performed cardiac surgeries worldwide. Despite surgical advancements, a significant proportion of patients experience psychological distress following surgery, with depression being particularly common. Current evidence regarding the effectiveness of preoperative psychological interventions in improving postoperative mental health outcomes remains inconclusive.
View Article and Find Full Text PDFCogn Emot
September 2025
Department of Psychology, University of Georgia, Athens, GA, USA.
Individuals with schizophrenia (SZ) experience difficulties across stages of emotion regulation. However, moderators of abnormalities at each stage have not been systematically examined, limiting the development of mechanism-based treatment approaches. In the current study, outpatients with SZ (n = 52) and healthy controls (CN) (n = 55) completed six days of ecological momentary assessment (EMA) assessing emotional experience, emotion regulation, and moderators including: arousal, emotional awareness, ability to describe emotions, interoception, acceptance, emotion regulation knowledge, and cognitive ability.
View Article and Find Full Text PDFFront Psychiatry
August 2025
Department of Clinical Psychology and Psychotherapy of Childhood and Adolescence, Johannes Gutenberg University Mainz, Mainz, Germany.
Unlabelled: This systematic review and meta-analysis synthesize current research on interoception in individuals with autism spectrum disorder (ASD) across the lifespan. A total of 31 studies meeting stringent inclusion and quality criteria were identified, incorporating both descriptive and numerical analyses of cardiac interoceptive accuracy (cIA), interoceptive sensibility (IS), and interoceptive awareness (IAW) in children, adolescents, and adults with ASD. The meta-analysis of five adult studies using comparable assessment tools found no significant differences in cIA between adults with ASD and neurotypically developed (NTD) controls [ = 5; = -.
View Article and Find Full Text PDFAppl Psychol Health Well Being
October 2025
Department of Psychology, University of Graz, Austria.
Mindfulness practices, such as the body scan, could enhance interoception. While prior research shows promise for its effects on interoceptive sensibility (IS; subjective experience of bodily cues) and accuracy (IAcc; accurate detection of bodily signals), studies often use a limited set of interoceptive variables or apply small samples. In two pre-registered randomized trials, we examined a 2-week daily auditory body scan intervention vs.
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