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http://dx.doi.org/10.3988/jcn.2022.0433 | DOI Listing |
Cureus
August 2025
Neurology, Palmetto General Hospital, Miami, USA.
Transverse myelitis (TM) is an inflammatory disorder of the spinal cord often associated with autoimmune diseases, such as systemic lupus erythematosus (SLE) or neuromyelitis optica spectrum disorder (NMOSD); however, it is rarely linked to rheumatoid arthritis (RA). We present the case of a 28-year-old woman with subacute ascending numbness, lancinating pain, and bilateral lower extremity weakness resulting in significant functional impairment. Despite upper motor neuron signs on examination and supportive cerebrospinal fluid findings, including elevated gamma globulins and positive myelin basic protein, spinal MRI remained negative.
View Article and Find Full Text PDFActa Neurochir (Wien)
August 2025
Department of Neurosurgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Insular epilepsy after encephalitis is often drug-resistant and MRI-negative, limiting resection due to eloquent cortex involvement. We describe a case in which radiofrequency thermocoagulation (RFTC) was applied to disconnect the propagation network (PN) identified by stereoelectroencephalography. In a woman with focal to bilateral tonic-clonic seizures, the epileptogenic network (EN) was in the left insula and temporal operculum, and the PN spread to the perirolandic area.
View Article and Find Full Text PDFClin Neurol Neurosurg
October 2025
Department of Neurology and Laboratory of Neuroimmunology, and the Agnes-Ginges Center for Neurogenetics, Hadassah, Medical Center, Ein-Kerem, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel. Electronic address:
Background: Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD) is an inflammatory demyelinating disorder of the central nervous system. While spinal MRI in MOGAD typically reveals longitudinally extensive transverse myelitis lesions, often involving the conus, rare cases of clinical myelitis without radiological abnormalities have been reported. This study aimed to characterize such MRI-negative presentations in MOGAD and compare them with previously published cases.
View Article and Find Full Text PDFJ Neurol Sci
August 2025
Epilepsy Center, Neurological Institute, Cleveland Clinic, United States of America. Electronic address:
Objective: This study investigates the potential of magnetic resonance fingerprinting (MRF) as a non-invasive method to differentiate epileptogenic from non-epileptogenic cortical malformations.
Methods: Sixty-nine subjects were included: four patients with complex cortical malformations who underwent detailed pre-surgical assessments including Stereo-EEG (SEEG) and/or subsequent surgery, 17 with histopathologically confirmed FCD II, and 48 healthy controls (HC). All subjects underwent a whole-brain 3 T MRF acquisition, the reconstruction of which generated T1 and T2 relaxometry maps.
Orthop J Sports Med
August 2025
Department of Orthopedic Surgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, PR China.
Background: Several studies on the relationship between morphological parameters and posterior cruciate ligament (PCL) injury have already been conducted. However, few studies focused on the association between the morphology of the tibial ridge and PCL injury, especially in isolated PCL cases.
Purpose: To retrospectively compare tibial ridge morphology between patients with isolated PCL tear and age/sex-matched controls with intact PCL after a knee injury.