MALDI and Trace Metal Analysis in Age-Related Macular Degeneration.

Methods Mol Biol

Centre for Mass Spectrometry Imaging, Biomolecular Sciences Research Centre, Sheffield Hallam University, Sheffield, UK.

Published: July 2023


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Article Abstract

Age-related macular degeneration (AMD) remains one of the most prevalent causes of blindness throughout the world. Key to prevention of AMD is furthering the understanding of its pathology. In recent years, both the proteins within the innate immune system and essential and non-essential metals have been implicated in the pathology of AMD. Herein, a multidisciplinary and multimodal methodology has been taken to further our understanding of the role of the innate immune proteins and the essential metals within mouse ocular tissue.

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http://dx.doi.org/10.1007/978-1-0716-3319-9_1DOI Listing

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