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Nanosensors are nanoscale devices that measure physical attributes and convert these signals into analyzable information. In preparation, for the impending reality of nanosensors in clinical practice, we confront important questions regarding the evidence supporting widespread device use. Our objectives are to demonstrate the value and implications for new nanosensors as they relate to the next phase of remote patient monitoring and to apply lessons learned from digital health devices through real-world examples.
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http://dx.doi.org/10.2217/pme-2022-0065 | DOI Listing |
Food Chem
September 2025
School of Food Science and Engineering, Wuhan Polytechnic University, Wuhan 430028, China.
A versatile fluorescent molecularly imprinted nanosensor (MIPs@O-CDs) for profiling ciprofloxacin (CIP) was innovatively developed using a controllable post-imprinting modification strategy. High-affinity molecularly imprinted polymers (MIPs) as recognition elements granted nanosensor favorable anti-interference. Bright orange-emission carbon dots (O-CDs) as signal transducers demonstrated prominent reverse fluorescence response to CIP due to inner filter effect, ameliorating detection sensitivity and accuracy.
View Article and Find Full Text PDFPharmaceutics
July 2025
Department of Basic Medical Sciences, Health Sector, Galala University, Suez 43511, Egypt.
Nanotechnology is revolutionizing medicine by enabling highly precise diagnostics, targeted therapies, and personalized healthcare solutions. This review explores the multifaceted applications of nanotechnology across medical fields such as oncology and infectious disease control. Engineered nanoparticles (NPs), such as liposomes, polymeric carriers, and carbon-based nanomaterials, enhance drug solubility, protect therapeutic agents from degradation, and enable site-specific delivery, thereby reducing toxicity to healthy tissues.
View Article and Find Full Text PDFAdv Sci (Weinh)
August 2025
CPCV, Département de chimie, École normale supérieure, PSL University, Sorbonne Université, CNRS, 24, rue Lhomond, Paris, 75005, France.
In cells, many small molecules are membrane-permeant. This feature opens a road to analyze their flux of production or consumption by quantitatively interpreting the map of their extracellular concentration within a reaction-diffusion frame. Here, this approach is implemented with a new wide-field lifetime imaging protocol applied to single microalgae cells sparsely deposited on an agarose pad loaded with a luminescent dioxygen (O) nanosensor.
View Article and Find Full Text PDFBiosensors (Basel)
August 2025
Dipartimento di Scienze e Tecnologie Biologiche ed Ambientali (Di.S.Te.B.A.), Università del Salento, Via per Monteroni, 73100 Lecce, LE, Italy.
Molecularly imprinted polymers (MIPs) have emerged as robust, cost-effective analogues of bioreceptors, offering high selectivity and stability. When applied in sensors, one key step is the integration of MIPs with the transducer, which critically affects sensor performance. Demanding challenges come when such integration involves nanoscaling processes, meaning that the transducer is nanostructured or the MIP itself is nanosized on a bulk transducer.
View Article and Find Full Text PDFSci Rep
August 2025
Department of Physics, Hariom Saraswati PG College Dhanauri, Haridwar, Haridwar, Uttarakhand, 247667, India.
An extensive study on the laser power limiting behavior of para-aminobenzoic acid (PABA) combined with silver nanoparticles (PABA + AgNPs) was done and reported in this article. The XRD spectra for PABA + AgNPs confirm its crystalline structure. The absorption spectra of AgNPs and PABA + AgNPs indicate complete stability of the samples.
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