98%
921
2 minutes
20
Air pollution exposure plays a key role in the alteration of gene expression profiles, which can be regulated by microRNAs, inducing the development of various diseases. Moreover, there is also evidence of sensitivity of miRNAs to environmental factors, including tobacco smoke. Various diseases are related to specific microRNA signatures, suggesting their potential role in pathophysiological processes; considering their association with environmental pollutants, they could become novel biomarkers of exposure. Therefore, the aim of the present work is to analyse data reported in the literature on the role of environmental stressors on microRNA alterations and, in particular, to identify specific alterations that might be related to the development of airway diseases so as to propose future preventive, diagnostic, and therapeutic strategies.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10304259 | PMC |
http://dx.doi.org/10.3390/life13061375 | DOI Listing |
Int J Soc Psychiatry
September 2025
Department of Psychiatry, King George's Medical University, Lucknow, Uttar Pradesh, India.
Background: Climate distress is a psychological reaction to adverse weather events and climate change. These events can increase people's vulnerability to develop psychiatric disorders like anxiety, depression, and PTSD particularly in disaster-prone regions like India.
Aim: To explore the relationship between climate distress and psychological impact with a particular emphasis on women, elderly, and other at risk populations who owing to their health vulnerabilities, lack of resources or social roles that make them dependent on others, experience stress in the face of climate change.
Medicine (Baltimore)
September 2025
Department of Basic Medicine and Law, School of North Sichuan Medical College, Nanchong, Sichuan, China.
Epidemiological studies have already established associations between air pollutants and adverse health outcomes, but the causal associations between air pollutants and chest pain (CP) and gingival pain (GP) remain unclear. This study aimed to explore the potential causal effects of air pollutants on CP and GP. Utilizing genome-wide association study summary statistics from European-ancestry populations, we conducted bidirectional two-sample Mendelian randomization (MR) analyses.
View Article and Find Full Text PDFJ Am Chem Soc
September 2025
State Key Joint Laboratory of Environment Simulation and Pollution Control, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.
Recently, the atmospheric aerosol surface, which is reported to be quite acidic, is recognized as an important microreactive medium for atmospheric chemistry, profoundly impacting air quality and global climate. Nevertheless, the molecular-level understanding of the effect of surface-bound acids on atmospheric chemical reactions remains limited. Herein, the reactions between CO and NH/amines at the air-water interface with organic acids are investigated using combined molecular dynamic simulations and quantum chemical calculations.
View Article and Find Full Text PDFArch Environ Contam Toxicol
September 2025
Department of Environmental Engineering, Faculty of Engineering and Natural Sciences, Bursa Technical University, Mimar Sinan Mahallesi Mimar Sinan Bulvarı Eflak Caddesi No:177, 16310, Yıldırım, Bursa, Turkey.
This study investigates airborne concentrations of six insecticides widely used on crops grown in agricultural, semi-urban, and rural areas of Bursa Province, Türkiye. Sorbent-impregnated passive air samplers (SIP-PASs), consisting of polyurethane foam (PUF) disks impregnated with XAD-2 resin, were deployed at ten strategically selected sites representing diverse agricultural and demographic profiles within the province. Analytes were quantified using gas chromatography-mass spectrometry (GC-MS) for depuration compounds and liquid chromatography-tandem mass spectrometry (LC-MS/MS) for target insecticides.
View Article and Find Full Text PDFProg Mol Biol Transl Sci
September 2025
Heidelberg Institute of Global Health (HIGH), Faculty of Medicine and University Hospital, Heidelberg University, Heidelberg, Germany. Electronic address:
Climate change poses a growing threat to human health, increasing exposure to extreme environmental conditions. Wearable biosensors provide real-time monitoring of physiological responses to heat stress, including cardiovascular strain, thermoregulatory disruptions, sleep disturbances, and biomarkers of heat-related illnesses. These devices also assess behavioural adaptations, such as reduced physical activity, offering insights into physiological resilience and susceptibility.
View Article and Find Full Text PDF