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Group A Streptococcus is one of the leading causes of otorrhea. The performance of rapid antigen tests in 256 children with otorrhea showed excellent sensitivity, 97.3% (95% confidence interval: 90.7%-99.7%), and specificity, 100% (95% confidence interval: 98.0%-100%). In a period of increasing invasive and noninvasive group A Streptococcus infections, an early diagnosis could be useful.
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http://dx.doi.org/10.1097/INF.0000000000004009 | DOI Listing |
Clin Exp Dent Res
October 2025
Tasmanian School of Medicine, College of Health and Medicine, University of Tasmania, Hobart, Tasmania, Australia.
Objectives: Oral health is an important aspect of quality of life for older people, especially those with dementia. The impact of an active oral hygiene program on the oral microbiome was explored in a group of older participants (average age 84 years old) with dementia against a separate control group whose oral hygiene followed the status quo.
Materials And Methods: The oral cavity bacteriomes and mycobiomes were assessed from swabs of cheek, gum, and tongue surfaces.
Can J Infect Dis Med Microbiol
August 2025
Department of Laboratory Medicine, Daejeon Eulji Medical Center, Eulji University, Daejeon, Republic of Korea.
This study aims to determine the molecular features and antimicrobial resistance of (Group B streptococcus, GBS) causing invasive and noninvasive infections in Korean adults. Sequence type (ST), capsular serotype, pilus island typing, and antimicrobial susceptibility were analyzed for GBS isolates obtained at a hospital laboratory that processed the primary clinical specimens collected from Korean adults between 2021 and 2024. Among the 90 isolates, Serotype VIII (34.
View Article and Find Full Text PDFFront Microbiol
August 2025
Department of Allergy, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.
Introduction: Hepatic sinusoidal obstruction syndrome (HSOS) is a vascular liver disease with a high mortality rate, and treatment methods are limited. Rivaroxaban is an oral anticoagulant. This study aimed to investigate the pharmacological effect and potential mechanism of rivaroxaban on HSOS.
View Article and Find Full Text PDFInt J Gen Med
August 2025
Department of Pediatrics, The Affiliated Suqian Hospital of Xuzhou Medical University, Suqian, People's Republic of China.
Purpose: The gut microbiota plays a crucial role in bilirubin metabolism in neonates. The phototherapy threshold assesses the need for clinical intervention in neonatal hyperbilirubinemia (NH). This study aimed to investigate gut microbiota alterations in neonates with NH meeting the phototherapy threshold.
View Article and Find Full Text PDFeGastroenterology
August 2025
Serviço de Endocrinologia, Diabetes e Metabolismo, ULS São João, Porto, Portugal.
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is the leading cause of chronic liver disease globally, with rising prevalence linked to metabolic syndrome (MetS). Excessive liver fat accumulation (steatosis) worsens disease progression and MASLD prognosis. Moreover, gut microbiota dysbiosis might promote steatosis, accelerating the disease progression to severe stages.
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