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Background: Facial erythema is a common problem among patients visiting dermatologists. However, data on the clinical characteristics of facial erythema in healthy people are lacking. We aimed to compare and analyze the severity and pattern of facial vascularity in healthy subjects based on their age and gender.
Materials And Methods: This study included 198 Korean volunteers (126 females and 72 males) with Fitzpatrick skin types II, III, or IV. Fourteen different anatomical areas on the face were divided into facial erythema units. Each unit was scored from one (least erythematous) to five (most erythematous) according to the observed level of erythema on the red images implemented as hemoglobin content. We also evaluated the presence of facial telangiectatic macules.
Results: On average, the perinasal, nasal, and cheek units were the most hypervascular regions. In contrast, the degree of facial erythema was lowest in the labial (perioral), neck, and temporal regions. The average value of erythema was higher in males than in females. Additionally, the severity of erythema tended to increase with age. In both males and females, the number of telangiectatic macules increased with age.
Conclusions: We analyzed the clinical characteristics of erythema in healthy subjects with Fitzpatrick skin types II, III, or IV in the Korean population. This study is expected to be used to identify the neurovascular pathogenesis of the most common regions of facial dermatosis in the future.
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http://dx.doi.org/10.1111/srt.13344 | DOI Listing |
Contour Tunable Resurfacing Laser (TRL™) is an erbium: yttrium aluminum garnet (YAG) fully ablative laser commonly used to treat the delicate lower eyelid skin for undereye rejuvenation. Post-treatment patients experience discomfort and extensive downtime. This pilot study incorporated an innovative post-procedure treatment that addresses patient concerns to skin rejuvenation procedures to improve patient relief and recovery, while improving patient retention.
View Article and Find Full Text PDFBackground: Energy-based devices are commonly used to improve the appearance of aging skin. Treatments can involve long recovery times, marked by pain, erythema, edema, and purpura, which is often a limiting factor in a patient’s willingness to undergo a procedure.
Objective: This study evaluated the safety and effectiveness of an Angiopoietin-1 derived QHREDGS peptide (Q-peptide) hydrogel and ointment, in comparison to a peptide-free control, in enhancing healing and patient satisfaction after radiofrequency microneedling (RFMN) treatment.
Dermatology
September 2025
Department of Clinical Pharmacology and Toxicology, University of Geneva, Geneva, Switzerland.
Introduction: Non-transient erythema (NTE) is a major feature of rosacea, but its clinical evaluation is subject to human investigator variability. The angiopoietin-TIE2 receptor tyrosine kinase pathway plays a key role in regulating vascular homeostasis, but was previously overlooked as a target for rosacea therapy. Angiopausin® is a patented plant-based ingredient identified through a molecular phytotherapy screening program as a positive inducer of the angiopoietin-TIE2 pathway, which is the "gatekeeper of vascular quiescence.
View Article and Find Full Text PDFClin Cosmet Investig Dermatol
August 2025
Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin Hospital, Bandung, West Java, Indonesia.
Post-acne erythema (PAE) is persistent erythema after acne vulgaris (AV) inflammatory lesions have resolved. Pulsed dye laser (PDL) is the gold standard for vascular lesions and is effective for PAE. Tranexamic acid (TA) can reduce vascular endothelial growth, angiogenesis, and inflammation by inhibiting plasminogen activity, and can be used in PAE treatment.
View Article and Find Full Text PDFCureus
August 2025
Internal Medicine, Larkin Community Hospital Palm Springs Campus, Hialeah, USA.
Periorbital cellulitis and angioedema can present with similar clinical features, posing a diagnostic challenge. We describe a case of a 71-year-old female patient with a past history of hypertension and diabetes who developed facial swelling and erythema following trauma. She was initially treated for periorbital cellulitis but was later found to have concurrent angioedema, likely triggered by antibiotics and herbal supplements.
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