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We describe a case of adenomyosis that reduced in size in a patient with lymphoma on receiving chemotherapy. A 48-year-old woman with worsening left flank pain was diagnosed with follicular lymphoma. [ 18 F]FDG PET/CT revealed multiple hypermetabolic lymph nodes in the bilateral cervical, axillary, mediastinal, mesenteric, retroperitoneal, iliac, and inguinal regions. In addition, adenomyosis with mild hypermetabolism was demonstrated on [ 18 F]FDG PET/CT. The size and metabolism of adenomyosis decreased after chemotherapy with R-bendamustine; in addition, along with decrease in estradiol levels, the patient experienced amenorrhea and hot flushes. The patient was diagnosed with chemotherapy-induced early menopause.
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http://dx.doi.org/10.1097/RLU.0000000000004755 | DOI Listing |
World J Radiol
August 2025
Department of General Practice, Baiyang Community Health Service Center, Hangzhou 310000, Zhejiang Province, China.
Background: Signet ring cell carcinoma originating from the appendix is extremely rare, and the lack of specific clinical symptoms and imaging features makes preoperative diagnosis particularly challenging.
Case Summary: We report a case of a 49-year-old woman who presented with irregular vaginal bleeding lasting more than five months. Computed tomography (CT) and magnetic resonance imaging (MRI) revealed an enlarged appendix with a thickened wall and progressive enhancement after contrast administration.
Int J Gynaecol Obstet
September 2025
Department of Obstetrics and Gynecology, University Hospital, Angers, France.
Uterine fibroids (leiomyomas) and adenomyosis are among the most common benign gynecological conditions affecting women of reproductive age. These disorders are frequently associated with abnormal uterine bleeding, pelvic pain, pressure symptoms on adjacent pelvic organs, and potential infertility. The incidence of fibroids increases as women enter their third and fourth decades of life.
View Article and Find Full Text PDFWorld J Clin Cases
October 2025
Department of Obstetrics and Gynecology, Chonnam National University Medical School, Gwangju 61469, South Korea.
Background: Uterine adenomyosis and pulmonary endometriosis are exceptionally rare in adolescents and can pose significant diagnostic challenges due to their nonspecific clinical presentation and imaging features, which may mimic malignancy. Here, we describe a case of adenomyosis-associated uterine rupture (secondary to hemorrhagic necrosis) and concurrent pulmonary endometriosis in a 16-year-old girl initially suspected of having advanced uterine cancer.
Case Summary: A 16-year-old girl presented with acute abdominal pain and oliguria.
Cureus
July 2025
Obstetrics and Gynecology, Dignity Health East Valley, Obstetrics and Gynecology Residency Program, Gilbert, USA.
A 45-year-old female presented to the Emergency Department with acute right lower quadrant (RLQ) pain. Her past medical history was significant for heavy menstrual bleeding and moderate dysmenorrhea, though a diagnosis of endometriosis had never been established previously. Initial work-up revealed anemia and leucocytosis.
View Article and Find Full Text PDFCureus
July 2025
Department of Diagnostic Pathology, Kyoto University Hospital, Kyoto, JPN.
Adenosarcoma is a mixed epithelial and mesenchymal neoplasm composed of a malignant mesenchymal component and a benign Müllerian glandular component. Although the endometrium is the most common primary site, adenosarcoma can also occur in the cervix, ovaries, fallopian tubes, vagina, or other sites outside the genital tract. This report presents the case of a 59-year-old woman with intramural adenosarcoma, associated with adenomyosis and endometriosis.
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