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Purpose: Holmium:YAG laser lithotripsy requires high amperage power and has an upper limit of frequency and a minimal fiber size. The technology utilizing thulium-doped fiber offers low pulse energy settings and high pulse frequencies up to 2,400 Hz. We compared the novel SuperPulsed thulium fiber laser (SOLTIVE™; Olympus) to a commercially available 120 W Ho:YAG laser.
Materials And Methods: Bench-top testing was conducted with 125 mm standardized BegoStones (Bego USA). Time to ablate the stone into particles <1 mm was recorded for efficiency calculations. Finite energy was delivered, and resulting particle sizes were measured to determine fragmentation (0.5 kJ) and dusting (2 kJ) efficiencies. Remaining mass or number of fragments were measured to compare efficacy.
Results: SOLTIVE™ was faster at ablating stones to particles <1 mm (2.23±0.22 mg/s, 0.6 J 30 Hz short pulse) compared to Ho:YAG laser (1.78±0.44 mg/s, 0.8 J 10 Hz short pulse) (p<0.001). Following 0.5 kJ of energy in fragmentation testing, fewer particles >2 mm remained using SOLTIVE™ than Ho:YAG laser (2.10 vs. 7.20 fragments). After delivering 2 kJ, dusting (1.05±0.08 mg/s) was faster using SOLTIVE™ (0.1 J 200 Hz short pulse) than 120 W 0.46±0.09 mg/s (0.3 J 70 Hz Moses) (p=0.005). SOLTIVE™ (0.1 J 200 Hz) produced more dust particles <0.5 mm (40%) compared to 24% produced by the P120 W laser at 0.3 J 70 Hz Moses and 14% at 0.3 J 70 Hz long pulse (p=0.015).
Conclusions: The efficacy of SOLTIVE™ is superior to the 120 W Ho:YAG laser by producing smaller dust particles and fewer fragments. Further studies are warranted.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10172052 | PMC |
http://dx.doi.org/10.4111/icu.20230071 | DOI Listing |
Urol Ann
July 2025
Department of Urology, Shri BM Patil Medical College Hospital and Research Centre, Vijayapura, Karnataka, India.
Objectives: The objective of the study was to analyze the efficacy and safety of superpulsed thulium fiber laser (TFL) lithotripsy and to identify the ideal laser settings.
Methodology: Patients with ureteric stones were included prospectively. We performed Lithotripsy by superpulsed TFL 400 micron laser fiber, UROLASE SP+ (60W), IPG IRE POLUS Russia.
Urol Case Rep
July 2025
Department of Urology, Centre Hospitalier de Luxembourg, 4 Rue Nicolas Ernest Barblé, Rollingergrund-North Belair 1210, Luxembourg.
Giant bladder stones are uncommon in our industrialized countries specially in the female and pediatric population. Cystolithotomy has always been the treatment of choice. We present the case of a 14 years old girl with a 75 × 53mm bladder stone discovered by ultrasound and confirmed by MRI.
View Article and Find Full Text PDFJ Endourol
August 2025
Department of Urology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
High-powered lasers have been hypothesized to cause kidney injury; however, no human studies have confirmed or quantified this damage. Our objective was to identify and quantify damage and explore factors affecting degree of injury in patients undergoing retrograde intrarenal surgery (RIRS) with thulium fiber laser (TFL) and Holmium:YAG (Ho:YAG) lasers. Patients undergoing RIRS for unilateral nonobstructing renal stones were randomized to receive lithotripsy with either a 60 W SuperPulse TFL or 120 W pulse-modulated Ho:YAG laser.
View Article and Find Full Text PDFPurpose: Recent developments in high-power systems and the super-pulsed thulium fiber laser (TFL) promise enhanced efficiency but raise concerns about thermal safety. This study examines the intrarenal temperature profiles of Ho: YAG and TFL systems including the advanced fragmentation pulse (AFP) mode under simulated conditions.
Methods: A custom-designed kidney and ureter model was used to measure intrarenal temperature changes during laser activation.
Eur J Med Res
May 2025
Department of Urology, Guangxi Hospital Division of The First Affiliated Hospital, Sun Yat-Sen University, No.3 Fozi Ling Road, Qingxiu District, Nanning, 530022, Guangxi, China.
Objectives: The purpose of this review is to compare the effectiveness of SuperPulsed thulium fiber laser (SP TFL) and holmium:yttrium-aluminum-garnet (Ho:YAG) laser in lithotripsy, with the aim of evaluating the differences between the two in key indicators, such as lithotripsy efficiency and safety, and providing reference for clinical selection of better lithotripsy methods.
Methods: By searching multiple authoritative medical databases (PubMed, Embase, and Web of Science databases) and including the results of relevant clinical studies and laboratory studies, the indexes involving SP TFL and Ho:YAG lasers in the included literature were analyzed.
Results: We found a total of 24 relevant pieces of literature.