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Periodontal disease in ruminants is common and occurs in farmed and wild animals. Periodontal lesions can result from the secretion of endotoxins by pathogenic bacteria and as consequences of immune system activity. Three main types of periodontitis have been described. The first is chronic inflammation involving mainly premolars and molars-periodontitis (PD). The second type is an acute inflammatory reaction occurring with calcification of the periosteum of the jawbone and swelling of the surrounding soft tissues (Cara inchada, CI-"swollen face"). Finally, a third type, similar to the first but located in the incisor area, is called "broken mouth" (BM). Etiological variation between the different types of periodontitis is indicated. This particularly manifests in the composition of the microbiome, which is characteristic of the different forms of periodontitis. The widespread detection of lesions has drawn attention to the current nature of the problem.
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http://dx.doi.org/10.3390/ijms24119763 | DOI Listing |
Braz Oral Res
September 2025
Universidade de São Paulo - USP, Bauru School of Dentistry, Department of Biological Sciences, Bauru, SP, Brazil.
Angiotensin II (Ang II) releases inflammatory mediators from several cell types. The objective of this study was to investigate the potential of Ang II to induce mRNA expression of inflammatory mediators in primary cultured fibroblast-like cells isolated from gingival and periodontal ligament tissues. A synergistic effect of co-treatment with Ang II and Interleukin-1β (IL1β) on the mRNA expression of inflammatory mediators was explored.
View Article and Find Full Text PDFJ Oral Biol Craniofac Res
August 2025
Neura Integrasi Solusi, Jl. Kebun Raya No. 73, Rejowinangun, Kotagede, Yogyakarta, 55171, Indonesia.
Background: Periodontal disease is an inflammatory condition causing chronic damage to the tooth-supporting connective tissues, leading to tooth loss in adults. Diagnosing periodontitis requires clinical and radiographic examinations, with panoramic radiographs crucial in identifying and assessing its severity and staging. Convolutional Neural Networks (CNNs), a deep learning method for visual data analysis, and Dense Convolutional Networks (DenseNet), which utilize direct feed-forward connections between layers, enable high-performance computer vision tasks with reduced computational demands.
View Article and Find Full Text PDFFront Dent Med
August 2025
Department of Otorhinolaryngology Head and Neck Surgery, Ningbo Yinzhou No. 2 Hospital, Ningbo, Zhejiang, China.
Background: With the increase in the resident population and the number of children in Ningbo, as well as the growing demand for oral health care, the number of children's dental emergencies has been increasing year by year. This trend not only increases the pressure on medical resources, but also puts higher demands on the level of children's oral emergency care. In order to better guide the diagnosis and treatment of common and frequent diseases in paediatric oral emergency care, and to improve the efficiency of the use of medical resources.
View Article and Find Full Text PDFMinerva Dent Oral Sci
September 2025
Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, India.
Introduction: Dental health and overall well-being are greatly impacted by temporomandibular disorders (TMDs), which encompass a spectrum of illnesses that impact the temporomandibular joint and its surrounding structures. The use of dental prostheses, including complete and partial dentures, is common among individuals with missing teeth. However, the association between denture types and the prevalence of TMD remains a subject of interest and concern in the field of oral health.
View Article and Find Full Text PDFNaunyn Schmiedebergs Arch Pharmacol
September 2025
School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, China.
Periodontal disease (PD) is a common and complex oral health problem that affects teeth and gums, leading to tooth loss, misalignment, and infection, with significant impact. Identifying the cause and developing new treatments is crucial. This study employed Mendelian randomization (MR), single-cell RNA sequencing (scRNA-seq), and integrated transcriptomics to identify key gene signatures associated with periodontitis.
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