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Background: Long-term follow-up of single implants and crowns is scarce, especially when inserted using flapless surgery.
Aim: Evaluate survival, peri-implantitis incidence, and technical/biologic complications of solitary implants/crowns after 10-12 years of function.
Material And Methods: 49 patients with 53 single implants, initially operated with a one-stage flap (F) or flapless (FL) surgery and delayed loading, were recalled. Implant survival, radiographic bone-level changes compared to baseline, peri-implant health, and soft tissue aesthetics were registered. Differences in implant level between and within groups were statistically tested using the Mann-Whitney U-Test and Wilcoxon Signed Ranks Test, respectively.
Results: 36 patients with 40 implants were reassessed, yielding 100% implant and 97.5% crown survival. The bone loss in F ( = 19) was 0.56 mm (SD 0.89; range -0.9-2.02) and -0.85 mm (SD 0.98; range -2.84-0.53) in FL ( = 21), indicative of bone gain in FL ( = 0.003), the latter due to a difference at baseline but bone-level was comparable ( = 0.126). Groups were comparable for probing pocket depth (PPD); (3.32 vs. 3.19 mm), Bleeding Index (BI); (0.15 vs. 0.22), and gingival recession; (0.38 vs. 0.17 mm). According to international criteria, the peri-implantitis incidence was 0%, but 32.5% of the implants/crowns experienced biological or technical complications irrespective of surgical technique.
Conclusions: Solitary implants and crowns show good long-term clinical outcomes and peri-implant health. Flapless surgery is a good alternative to conventional in straightforward cases with sufficient bone volume and proper treatment planning.
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http://dx.doi.org/10.3390/jcm12113668 | DOI Listing |
J Neurosci
September 2025
Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Human speech perception is multisensory, integrating auditory information from the talker's voice with visual information from the talker's face. BOLD fMRI studies have implicated the superior temporal gyrus (STG) in processing auditory speech and the superior temporal sulcus (STS) in integrating auditory and visual speech, but as an indirect hemodynamic measure, fMRI is limited in its ability to track the rapid neural computations underlying speech perception. Using stereoelectroencephalograpy (sEEG) electrodes, we directly recorded from the STG and STS in 42 epilepsy patients (25 F, 17 M).
View Article and Find Full Text PDFJ Prosthet Dent
September 2025
Full Professor and Department Head, Department of Prosthodontics, University of Heidelberg, Heidelberg, Germany.
Statement Of Problem: Despite high survival rates of implant-supported single crowns, retention loss remains common and decementation of crowns can compromise long-term stability, patient satisfaction, and treatment costs. Limited long-term evidence on cement type, abutment design, and materials requires further research to optimize clinical outcomes.
Purpose: The aim of this retrospective clinical study was to analyze the survival and decementation rates of zirconia and metal-ceramic implant-supported crowns in combination with different abutments (prefabricated or custom and unabraded or airborne-particle abraded).
JACC Cardiovasc Interv
September 2025
The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Background: Previous trials have demonstrated increased 5-year risks for adverse clinical events after coronary artery implantation of poly-l-lactic acid-based bioresorbable scaffolds (BRS) compared with cobalt chromium (CoCr) everolimus-eluting stents (EES).
Objectives: The aim of this study was to evaluate the 5-year clinical outcomes of the novel sirolimus-eluting NeoVas BRS compared with CoCr EES.
Methods: A total of 560 patients with single de novo native coronary artery lesions with reference vessel diameter 2.
Ann Vasc Surg
September 2025
Division of Vascular Surgery, 1(st) Surgical Department, Faculty of Health Sciences, Aristotle University, Papageorgiou General Hospital, Thessaloniki, Greece.
Introduction: Nitides™ (Alvimedica, Istanbul, Turkey) is a novel polymer-free stent, which elutes Amphilimus™; a combination of sirolimus and long chain fatty acids. Aim of this prospective single-center study is to assess the efficacy and 12-months outcomes of patients with femoropopliteal arterial disease, who underwent successful angioplasty with implantation of Amphilimus™-eluting stents Nitides™.
Methods: Patients with peripheral arterial disease who underwent angioplasty of the femoropopliteal segment with DES Nitides™ from August 2021 to February 2024 were included in the study.
Biomaterials
September 2025
Medical Research Institute, Department of Orthopedics, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, China. Electronic address:
Contrary to the traditional strengthening route by adding multiple & high-dosage alloying elements, we here explored extremely compositional and phase-constituent "simplification" in rare earth (RE) containing biodegradable magnesium alloys for better biocompatibility. An ultra-lean Mg-0.1Pr alloy with a multiscale microstructure has been developed through casting and extrusion, which showed well-balanced performances that match the commercial Mg-based orthopedic products.
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