Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Objective: This study aims to analyze risk factors for central lymph node metastasis (CLNM) in patients with small papillary thyroid carcinoma (PTC).
Methods: The clinicopathologic data of 375 patients with small PTC admitted to the Affiliated Hospital of Inner Mongolia Medical University from January 2017 to December 2020 were analyzed retrospectively. The patients were divided into two groups, namely, CLNM (n = 177) and non-CLNM (n = 198) groups. Relevant data from the two groups were analyzed using the chi-square test, logistic regression analysis, and the receiver operating characteristic (ROC) curve.
Results: The CLNM rate of the 375 patients with small PTC was 47.2%. The chi-square test revealed that CLNM status was correlated with a patient's gender and age as well as tumor size, number of lesions, and invasion of the thyroid capsule (P < 0.05), but not with BRAF gene mutation, Hashimoto's thyroiditis (HT), or nodular goiter. Multivariate analysis indicated significant differences in gender, maximum tumor diameter, multifocality, and thyroid adventitial infiltration between the two groups (all P < 0.05) but no significant difference between the two groups in regard to HT and nodular goiter. The ROC curve suggested that age ≤ 26.5 years and maximum tumor diameter ≥ 0.75 cm were thresholds for increased risk of CLNM.
Conclusions: Lymph node metastasis in the central area of small PTC is associated with multiple factors. Careful examination, analysis, and evaluation of these factors can help in developing accurate individualized treatment strategies.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244229 | PMC |
Publication Analysis
Top Keywords
Similar Publications
Evaluating Long-Term Effectiveness of Cystic Fibrosis Modulator Therapies After Rapid Adoption: A Dual-Approach Study.
Ann Am Thorac Soc
September 2025
Erasmus MC, Rotterdam, Zuid-Holland, Netherlands.
Rationale: Modulator therapies like ivacaftor have revolutionized clinical management of cystic fibrosis (CF), showing marked short-term benefits in trials but heterogeneous findings in long-term observational studies. Since newer modulators have become the standard of care for the majority living with CF in the U.S.
View Article and Find Full Text PDFEffect of C-reactive protein and serum amyloid A point-of-care testing on antibiotic prescribing for acute respiratory-tract infections at village clinics in China: A study protocol for a cluster randomised controlled trial.
PLoS One
September 2025
Department of Social Medicine and Health Management, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Background: Antimicrobial resistance is a globally recognised public health threat. In rural China, antibiotic use is common for acute respiratory infections (ARIs), which include symptoms such as coughing and fever that are most likely viral infections but with a small proportion as bacterial infections. This study aims to evaluate the effectiveness of a comprehensive intervention based on C-reactive protein and serum amyloid A point-of-care testing (CRP&SAA POCT) in reducing the inappropriate use of antibiotics for ARIs in Chinese village clinics.
View Article and Find Full Text PDFSix Cases of Borealpox and Evidence of a Zoonotic Source-Alaska, 2020-2023.
Clin Infect Dis
September 2025
Section of Epidemiology, Alaska Division of Public Health, Anchorage, Alaska, USA.
Background: Borealpox virus (previously known as Alaskapox virus) is an Orthopoxvirus species first identified in a patient living near Fairbanks, Alaska, in 2015; the source of the patient's infection was unknown. Six additional borealpox cases have been identified through 2023.
Methods: We conducted interviews to ascertain travel history and potential exposures for the six patients, trapped small mammals for orthopoxvirus testing, and performed a phylogenetic analysis of viral DNA sequences.
Patient capital and green total factor productivity: Evidence from Chinese listed companies.
PLoS One
September 2025
School of Economics, Minzu University of China, Beijing, China.
This study applies Fisher's investment framework to investigate how patient capital affects firms' green total factor productivity (GTFP). Using panel data from Chinese listed companies over the period 2008-2023, we measure firm-level GTFP by employing a non-radial SBM directional distance function combined with the Malmquist-Luenberger productivity index. Our analysis, based on two-way fixed-effects models and instrumental variable regressions, reveals that an increase in patient capital significantly enhances firms' green total factor productivity.
View Article and Find Full Text PDFIn Vitro Intraluminal Gel Infusion: An Advanced Approach for Microscopic Analysis of Human Resistance Arteries.
J Vis Exp
August 2025
Physiology Unit, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases.
Resistance arteries, which include small arteries and arterioles, play essential roles in regulating blood pressure and tissue perfusion. Dysfunction in these arteries can lead to various cardiovascular conditions such as hypertension, atherosclerosis, and heart failure, as well as neurovascular conditions. The examination of human resistance arteries is crucial for understanding cardiovascular disease mechanisms and developing targeted therapeutic strategies.
View Article and Find Full Text PDF