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http://dx.doi.org/10.1097/JS9.0000000000000407 | DOI Listing |
Radiol Imaging Cancer
September 2025
Department of Radiation Oncology, Cancer Center, The First Affiliated Hospital, Sun Yat-sen University, 58 Zhongshan Road, Guangzhou, China 510080.
Purpose To develop and test a machine learning (ML)-based model that integrates preoperative variables for prediction of advanced-stage progression (ASP) after transarterial chemoembolization (TACE). Materials and Methods This multicenter retrospective study (ResearchRegistry.com identifier no.
View Article and Find Full Text PDFJ Immunother Cancer
August 2025
Department of Radiation Oncology, UPMC Hillman Cancer Center/University of Pittsburgh, Pittsburgh, Pennsylvania, USA
SU2C-SARC032 establishes addition of perioperative pembrolizumab as a new treatment option for high-risk localized extremity soft tissue sarcoma (STS). For patients with stage III undifferentiated pleomorphic sarcoma or dedifferentiated/pleomorphic liposarcoma, addition of neoadjuvant and adjuvant pembrolizumab to preoperative radiation therapy (RT) and surgery improved 2-year disease-free survival by 15% compared with RT and surgery alone. This commentary highlights key insights from the trial: (1) the cooperative activity between pembrolizumab and RT, (2) the need for biomarker-driven patient selection, and (3) the potential for circulating tumor DNA to guide adjuvant treatment decisions.
View Article and Find Full Text PDFObes Surg
August 2025
FMC Medical Center, Nakhon Ratchasima, Thailand.
Qiu et al. present a nomogram integrating demographic, anthropometric, and comorbidity variables to predict weight loss outcomes one year after bariatric surgery. While this tool has potential for patient counseling and shared decision-making, its applicability in heterogeneous clinical settings requires careful consideration.
View Article and Find Full Text PDFArthroscopy
August 2025
Saarland University Medical Center, Department of Orthopaedics and Orthopaedic Surgery, Kirrberger Str., Bldg. 37, 66421 Homburg/Saar, Germany. Electronic address:
In recent years, the addition of lateral extra-articular procedures (LEAPs) to primary and revision anterior cruciate ligament (ACL) reconstructions is recommended in appropriate indications. Possible indications for combined primary ACL reconstructions and LEAPs might be a preoperative high-grade pivot-shift, generalized ligamentous hyperlaxity, genu recurvatum, chronic injury (> 6 months) or patients with young age (< 25 years) who intend to return to high-demanding sporting activities such as pivot- or contact sport. Different LEAPs are described in the current literature.
View Article and Find Full Text PDFJ Gynecol Oncol
August 2025
Department of Radiology, Oslo University Hospital, Oslo, Norway.