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This report summarises the presentations and activities of the SELECTBIO Workshop on Rigor and Reproducibility in EV Research and Single EV Analysis held in San Diego, USA, in December 2021. The motivation for the session was the recognition that progress in the extracellular vesicle (EV) field is limited by the availability of rigorous and reproducible EV measurement tools. These tools are absolutely required for EVs to evolve from a research lab curiosity to something that will improve our ability to understand, diagnose, treat, and prevent disease. The program focused on guidelines for EV measurement and characterization as laid out in the recent MISEV2018 and MIFlowCyt-EV publications, their implementation in routine practice, and their continued evolution as new EV measurement technologies are introduced. The conclusion of the workshop was that more effort focused on pre-analytical issues and benchmarking of isolation methods is needed to strengthen collaborations and advance more effective biomarkers.
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http://dx.doi.org/10.20517/evcna.2022.28 | DOI Listing |
Rev Neurol
August 2025
Servicio de Neurología, Hospital Universitario 12 de Octubre, 28041 Madrid, Español.
Introduction: The advancement of artificial intelligence (AI), particularly generative AI, has significantly transformed the field of medicine, impacting healthcare delivery, medical education, and research. While the opportunities are substantial, the implementation of AI also raises important ethical and technical challenges, including risks related to data bias, the potential erosion of clinical skills, and concerns about information privacy.
Development: AI has demonstrated great potential in optimizing both clinical and educational processes.
Cell Mol Gastroenterol Hepatol
September 2025
Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Acta Psychol (Amst)
September 2025
Management Department, Faculty of Economics, Administrative, and Social Sciences, Alanya University, 07400, Alanya, Antalya, Turkiye. Electronic address:
Online communities such as Reddit offer neurodivergent individuals a unique space to express emotions, seek psychosocial support, and negotiate identity outside conventional social constraints. Understanding how these communities articulate and structure emotional discourse is essential for inclusive technology design. This study employed a hybrid natural language processing (NLP) framework that integrates lexicon-based sentiment analysis (VADER) with transformer-based topic modeling (BERTopic).
View Article and Find Full Text PDFPrim Health Care Res Dev
September 2025
Department of Primary Care, Local Health Authority of Modena, Modena, Italy.
Social disadvantage can result in healthcare gaps and primary care may be a suitable healthcare context to identify unmet social needs. A variety of screening tools exists but none of them is consolidated in clinical practice. After reviewing the available instruments, we conducted a rigorous translation and trans-cultural adaptation into Italian language of the EveryONE social need screening tool questionnaire of the American Academy of Family Physicians.
View Article and Find Full Text PDFFront Vet Sci
August 2025
Department of Medicine and Surgery, Faculty of Veterinary Medicine, University Complutense of Madrid, Madrid, Spain.
Introduction: embryo production (IVP) in the domestic cat () remains highly variable owing to intrinsic reproductive traits and the absence of fully standardized protocols.
Methods: We retrospectively analysed 108 IVP replicates produced under a single protocol (2020-2024) to quantify the effects of season, donor age and methodological parameters on oocyte yield and embryo development.
Results: Winter proved the most favourable season for both oocyte recovery and blastocyst formation, whereas spring, despite lower initial yields, achieved the greatest post-selection oocyte retention.