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Introduction: Intensive care unit (ICU) structural and spatial design may play a role in infection prevention and control.
Methods: Between 09/2021 and 11/2021 we performed an online survey among ICUs in Germany, Austria and Switzerland.
Results: A total of 597 (40%) of the invited ICUs answered the survey; 20% of the ICUs were built before 1990. The median number of single rooms with interquartile range is 4 (IQR 2-6). The median total room number is 8 (IQR 6-12). The median room size is 19 (IQR 16-22) m for single rooms and 31 (26-37.5) m for multiple bed rooms. Furthermore, 80% of ICUs have sinks and 86.4% have heating, ventilation, air conditioning (HVAC) systems in patient rooms. 54.6% of ICUs must store materials outside of storage rooms due to lack of space and only 33.5% have a room dedicated to disinfection and cleaning of used medical devices. Comparing ICUs built before 1990 and after 2011 we could show a slightly increase of single rooms (3 [IQR 2-5] before 1990 vs. 5 [IQR 2-8] after 2011; p < 0.001).
Discussion: A large proportion of German ICUs do not meet the requirements of German professional societies regarding the number of single rooms and size of the patient rooms. Many ICUs lack storage space and other functional rooms.
Conclusion: There is an urgent need to support the construction and renovation of intensive care units in Germany with adequate funding.
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http://dx.doi.org/10.1007/s00063-023-01022-x | DOI Listing |
J Oncol Pharm Pract
September 2025
Hematology/Oncology, Scripps Clinic, La Jolla, USA.
IntroductionDaratumumab is a therapeutic cornerstone of the management of multiple myeloma, exerting its anti-myeloma activity through targeting of the cell surface glycoprotein CD38 on plasma cells. While originally given intravenously, the subcutaneous formulation, daratumumab hyaluronidase injection (Dara SC), has been associated with non-inferior efficacy and lower infusion-related reaction rates (IRRs) in the treatment of multiple myeloma and light chain amyloidosis. A noted benefit of Dara SC is a short administration time; however, the optimal observation time post injection to ensure patient safety is unclear from the drug labeling.
View Article and Find Full Text PDFMinerva Anestesiol
September 2025
Tropical Biome et Immunopathologie CNRS UMR-9017, INSERM U1019, Université de Guyane, Cayenne, French Guiana.
Background: Extended delays in non-elective surgeries have been associated with suboptimal outcomes. The SARS-CoV-2 pandemic forced healthcare systems to adapt their setups for unscheduled procedures, leading, in our institution, to a reorganization from a setup with two dedicated operating rooms (ORs) at a central facility without dedicated teams to a temporary one with both dedicated teams and ORs during lockdown phase. This study evaluates the impact of this transitions on the time to surgery considering unscheduled procedures.
View Article and Find Full Text PDFMedicine (Baltimore)
August 2025
The Department of Obstetrics and Gynecology, Wuhan Third Hospital, Wuhan City, Hubei Province, China.
Postpartum depression is a mood disorder characterized by feelings of sadness, hopelessness, fatigue, and anxiety that persist beyond the typical "baby blues" period. This study examines the prevalence of puerperal depression and its associated obstetric factors. A total of 208 mothers who delivered in the obstetrics department of this hospital from January 2020 to December 2023 were followed up during the puerperium in this retrospective cohort study.
View Article and Find Full Text PDFInt J Pediatr Otorhinolaryngol
August 2025
Department of Otolaryngology - Head and Neck Surgery, Western University, Canada. Electronic address:
Objectives: The primary objective of this study was to evaluate international practice patterns related to environmental sustainability in pediatric otolaryngology ORs, with a focus on the use of single-use versus reusable supplies.
Methods: An electronic survey was distributed using REDCap to members of an international pediatric otolaryngology WhatsApp group (n = 324). The survey included multiple-choice, Likert-scale, and open-ended questions regarding drape, gown, and glove usage for adenotonsillectomy, ear tube insertion, and laryngoscopy/bronchoscopy procedures, and broader sustainability practices including barriers and enablers.
Cancers (Basel)
August 2025
The Department of General and Visceral Surgery, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health (BIH), Hindenburgdamm 30, 12203 Berlin, Germany.
: Gastric cancer is increasingly being diagnosed at early stages, enabling the application of curative oncological and surgical approaches. With the growing adoption of minimally invasive techniques, robotic surgery is gaining increasing prominence in the operating rooms. As described by Stoyanova et al.
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