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Article Abstract
Ozone (O) is ubiquitous in the environment and exposure to high levels of O has been associated with various respiratory diseases, such as asthma, emphysema, and bronchitis. Therefore, it is necessary to develop a simple and efficient detection method for monitoring O in the environment and living cells. In this study, an intramolecular charge-transfer (ICT) compound was designed and synthesized based on a phenol-type hemicyanine dye and 4-bromo-1-butene, which could specifically detect O in aqueous solution. Due to the ICT process, the absorption spectrum, fluorescence spectrum, and color of the probe hemicyanine-butyl-3-enyl (HCB) changed significantly and thus the rapid and sensitive detection of O was realized. The interaction between O and the probe HCB could be completed within 40 min, and the detection limit of O was as low as 2.15 × 10 mol L. Finally, the proposed method was successfully applied to the visual detection of O in a simulated O environment and living cells.
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