Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Download full-text PDF

Source
http://dx.doi.org/10.23736/S2724-6051.23.05354-5DOI Listing

Publication Analysis

Top Keywords

comment "animal
4
"animal model
4
model assessment
4
assessment design
4
design coated
4
coated mitomycin-eluting
4
mitomycin-eluting biodegradable
4
biodegradable ureteral
4
ureteral stent
4
stent intracavitary
4

Similar Publications

The taxonomic status of Oshmarin, Mamaev & Parukhin, 1961 () and Manter, 1963 is controversial due to overlap/confusion in distinctive diagnostic characteristics for each genus and morphological/allometric ambiguity among some of their representatives and/or within records of the same species. To address these in-depth, morphological descriptions, molecular characterizations, and species delimitation analyses were conducted using a combination of comparative morphology, molecular phylogeny, multivariate analyses, and host-parasite data. Following a comprehensive review, a refined restricted concept of and is proposed.

View Article and Find Full Text PDF

Harnessing artificial intelligence to address substance use disorders in critically ill adolescents: a synergistic approach.

Ann Intensive Care

September 2025

School of Computer Science and Technology, Hangzhou Dianzi University, No. 1158, No. 2 Road, Xiasha Higher Education Zone, Hangzhou, 310018, Zhejiang Province, China.

View Article and Find Full Text PDF

Inflammatory mitochondrial signalling and viral mimicry in cancer.

J Transl Med

September 2025

Department of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emilia, Bologna, BO, Italy.

Endogenous transposable elements (TEs) are receiving increasing attention as potential targets to develop novel immunostimulatory strategies against cancer. Indeed, the defective epigenetic suppression of TEs in malignant cells offers a therapeutic window to enable their re-activation with at least some degree of selectivity. In line with this notion, multiple clinically employed epigenetic modifiers such as DNA-demethylating agents have been shown to promote the re-expression of TEs in preclinical tumour models, hence driving powerful inflammatory responses that enables increased sensitivity of immunitary immune cells to immunotherapy with immune checkpoint inhibitors (ICIs).

View Article and Find Full Text PDF

The search for transformative medicines has continuously uncovered select diseases associated with the disruption of the endocannabinoid (eCB) signaling system in the brain and emphasized the therapeutic value of small molecules that rescue this signaling system. In this issue of JCI, Wang et al. report that genetic disruption of PPP2R1A function in mouse forebrain, a preclinical mouse model of neurodevelopmental disorders, resulted in pronounced impairment of eCB signaling.

View Article and Find Full Text PDF