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http://dx.doi.org/10.4103/IJO.IJO_3282_22 | DOI Listing |
J Biomater Appl
August 2025
Department of Pharmaceutical Technology, Jadavpur University, Kolkata, West Bengal, India.
One of the disadvantages of traditional ophthalmic formulations is their short residence time in the eye. An gel is recommended as a remedy, as it can be converted into a gel upon contact with the eye and adhere for an extended period. Tamarind seed polysaccharide (TSP) is non thermo-sensitive and possesses the necessary properties to be used as a vehicle for administering medication to the eye.
View Article and Find Full Text PDFClin Ophthalmol
March 2025
College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia.
Purpose: Diabetic macular edema (DME) is a major cause of vision loss in diabetes. This systematic review and meta-analysis aimed to evaluate the efficacy and safety of intravitreal bevacizumab (IVB) combined with topical timolol-dorzolamide versus dorzolamide alone in DME patients.
Patients And Methods: A literature search was conducted across multiple databases until March 2024.
J Curr Glaucoma Pract
January 2025
Medical Affairs, Poen Laboratories, Buenos Aires, Argentina.
Aim And Background: To assess the efficacy of 2% dorzolamide/0.5% timolol/0.2% brimonidine tartrate fixed combination (DTB-FC) eye drops in patients with intermediate glaucoma stage.
View Article and Find Full Text PDFInt Ophthalmol
January 2025
Chairman and Professor of Ophthalmology, Kasr Alainy Faculty of Medicine, Cairo University, Giza, Egypt.
Purpose: This study evaluated the efficacy, safety, and tolerability of a single-dose, preservative-free (PF) Dorzolamide/Timolol combination (Twinzol-SDU).
Methods: A 3-month single-arm, multicenter, prospective cohort study was conducted in Egypt between January 2021 and October 2022 on previously diagnosed and controlled patients with ocular hypertension and/or glaucoma. Efficacy was assessed using the change in intraocular pressure (IOP) after 6 and 12 weeks.