Publications by authors named "Krishnagopal Srikanth"

Purpose: Dry eye symptoms can substantially affect the quality of life and visual outcome. There are several studies on ocular surface changes reported in diabetic patients. There is limited literature defining the relationship between dry eye with diabetic retinopathy (DR).

View Article and Find Full Text PDF

Protein drugs are used for treating many diseases of the eye and the brain. The formidable blood neural barriers prevent the delivery of these drugs into the eye and the brain. Hence, there is a need for a protein drug delivery system to deliver large proteins across blood-neural barriers.

View Article and Find Full Text PDF

Coronavirus disease 19 (COVID-19) and its ophthalmic manifestations have been variably portrayed. We report a case of a 56-year-old female presenting with sudden-onset vision loss associated with painful extraocular muscle movements in both eyes following COVID-19. Visual acuity was counting fingers close to face.

View Article and Find Full Text PDF

Purpose: To report the spectrum and the factors affecting the visual outcome of ocular injuries associated with maxillofacial trauma.

Methodology: A prospective observational study was carried out from January 2019 to June  2020 on patients of maxillofacial trauma at a rural tertiary care centre, in Pondicherry, India. Detailed history was obtained.

View Article and Find Full Text PDF

Purpose: Pseudoexfoliation syndrome (PXS) is an age related microfibrillopathy characterized by deposition of whitish flaky material over various ocular tissues. PXS eyes are known to have thinner corneas and thus can lead to an underestimation in intraocular pressure measurement. The purpose of this study was to find if there is any variation in central corneal thickness and intraocular pressure in PXS eyes and if there was any relationship between them.

View Article and Find Full Text PDF

Aim:: To quantify the levels of nitric oxide, inducible nitric oxide synthase, and 3-nitrotyrosine in cataractous lenses of smokers and smokers who chewed tobacco in comparison with non-smokers and non-smokers who chewed tobacco.

Study Design:: A total of 80 cataractous lenses from smokers, non-smokers, smokers with tobacco chewing habit, and non-smokers with tobacco chewing habit were collected from the patients who had enrolled in the Department of Ophthalmology, Mahatma Gandhi Medical College & Research Institute, Puducherry.

Methods:: Levels of nitric oxide, inducible nitric oxide synthase, and 3-nitrotyrosine were quantified using commercially available enzyme-linked immunosorbent assay kits.

View Article and Find Full Text PDF

Introduction: Corneal thickness is an important and sensitive indicator of corneal health. It is useful in monitoring corneal diseases such as corneal oedema and keratoconus, and selecting patients for refractive surgery. Central Corneal Thickness (CCT) is a risk factor for Primary Open-Angle Glaucoma (POAG).

View Article and Find Full Text PDF
Article Synopsis
  • Macular disease is a major cause of low vision in the Western world, particularly affecting central vision and causing various visual distortions.
  • The study aimed to assess retinal sensitivity changes in macular diseases using microperimetry at a rural hospital, involving 84 eyes from 52 patients aged over 20.
  • Results indicated that the majority of cases were Age-Related Macular Degeneration (AMD), with the mean retinal sensitivity varying among different macular conditions, and a significant portion of eyes demonstrated stable fixation.
View Article and Find Full Text PDF

Sirsasana is a type of headstand postural yoga in which the body is completely inverted. It is performed with or without wall support. In this position, the body is held upright supported by the forearms, while the crown of the head rests lightly on the floor.

View Article and Find Full Text PDF

Introduction: Gonioscopy is the gold standard in assessing anterior chamber angles. However, interobserver variations are common and there is a need for reliable objective method of assessment.

Aim: To compare the anterior chamber angle by gonioscopy and Spectral Domain Optical Coherence Tomography (SD-OCT) in individuals with shallow anterior chamber.

View Article and Find Full Text PDF

Purpose: To evaluate the foveal and macular thickness in various degrees of myopia and its association with axial length in low, moderate and high degrees of myopia.

Design: A cross-sectional study was done in the Department of Ophthalmology, MGMCRI, Pondicherry, India.

Materials And Methods: One hundred and twenty five eyes eyes of 64 myopic subjects between the age group of 20-40 who fulfilled the inclusion criteria were selected and complete ophthalmic examination was done.

View Article and Find Full Text PDF

Expulsive suprachoroidal hemorrhage can be surgical or spontaneous. Spontaneous expulsive suprachoroidal hemorrhage (SESCH) is a rare entity. Most of the reported cases of SESCH were caused by a combination of corneal pathology and glaucoma.

View Article and Find Full Text PDF

Postoperative vision loss (POVL) after major non-ocular surgery is a very rare but devastating complication since it has the potential to cause bilateral, severe and permanent loss of vision. The common major procedures resulting in POVL are cardiac and spinal procedures. We are reporting two patients who presented with features of bilateral anterior ischaemic optic neuropathy after coronary artery bypass grafting.

View Article and Find Full Text PDF