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Objective: The classification of clinical note sections is a critical step before doing more fine-grained natural language processing tasks such as social determinants of health extraction and temporal information extraction. Often, clinical note section classification models that achieve high accuracy for one institution experience a large drop of accuracy when transferred to another institution. The objective of this study is to develop methods that classify clinical note sections under the SOAP ("Subjective", "Object", "Assessment" and "Plan") framework with improved transferability.
Materials And Methods: We trained the baseline models by fine-tuning BERT-based models, and enhanced their transferability with continued pretraining, including domain adaptive pretraining (DAPT) and task adaptive pretraining (TAPT). We added out-of-domain annotated samples during fine-tuning and observed model performance over a varying number of annotated sample size. Finally, we quantified the impact of continued pretraining in equivalence of the number of in-domain annotated samples added.
Results: We found continued pretraining improved models only when combined with in-domain annotated samples, improving the F1 score from 0.756 to 0.808, averaged across three datasets. This improvement was equivalent to adding 50.2 in-domain annotated samples.
Discussion: Although considered a straightforward task when performing in-domain, section classification is still a considerably difficult task when performing cross-domain, even using highly sophisticated neural network-based methods.
Conclusion: Continued pretraining improved model transferability for cross-domain clinical note section classification in the presence of a small amount of in-domain labeled samples.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168403 | PMC |
http://dx.doi.org/10.1101/2023.04.15.23288628 | DOI Listing |
J Healthc Sci Humanit
January 2024
Assistant Professor & Clinical Coordinator, Health Informatics Program, School of Health Professions, State University of New York Downstate Health Sciences University, 450 Clarkson Avenue, MSC 94, Brooklyn, NY 11203, (718) 270-7738, Fax: (718) 270-7739 Email:
COVID-19 variants continue to infect thousands of people even though the end of the pandemic was announced on May 11, 2023. Nextstrain CoVariants (CoVariants) genomic databases provide detailed information about more than 31 variants of COVID-19 viruses that have been identified through genomic sequencing, showing the mutations they carry. Mutated viruses may yield a negative result for a gene target using a PCR test that has a positive COVID-19 test result.
View Article and Find Full Text PDFJ Neurol Surg A Cent Eur Neurosurg
September 2025
Neurosurgery, University of Tsukuba Institute of Medicine, Tsukuba, Japan.
Background: Intracranial solitary fibrous tumors (SFTs) are rare mesenchymal tumors often presenting with dural-based lesions. These tumors can exhibit aggressive characteristics with high recurrence rates and extracranial metastasis. While SFTs occasionally invade venous sinuses, cases where the tumor arises within the venous sinus are rare.
View Article and Find Full Text PDFEur Arch Paediatr Dent
September 2025
Araçatuba School of Dentistry, São Paulo State University - UNESP, Araçatuba, Brazil.
Purpose: This systematic review provides a critical evaluation, synthesis of the existing literature on isotretinoin's effects on craniomaxillofacial bone.
Methods: Following the PRISMA guidelines and registered in PROSPERO, the review was conducted in August 2024 across various databases. Eligible in vivo studies were analysed for their assessment of isotretinoin's effects on craniomaxillofacial bone.
Radiology
September 2025
Department of Electrical, Electronic, and Information Engineering "Guglielmo Marconi", University of Bologna, Cesena, Italy.
Cureus
August 2025
Department of Radiotherapy Physics, Newcastle upon Tyne Hospitals National Health Service (NHS) Foundation Trust, Newcastle upon Tyne, GBR.
Introduction Stereotactic radiosurgery (SRS) is widely regarded as the standard of care after the resection of brain metastases in order to reduce local cavity recurrence risk. The objective of this study was to explore the reproducibility of published outcomes for patients receiving post-operative stereotactic radiosurgery (cavity SRS) in a National Health Service (NHS) setting for a non-selective series of patients. For our service, the median interval between surgery to cavity SRS (cSRS) is eight weeks, whereas similar timelines have been found to have a deleterious impact on survival in the published literature.
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