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Objective: Management of tracheostomized patients typically involves a conventional external humidification system (CEHS). CEHS are noisy, negatively impact patient mobility, and increases costs. Additionally, they prevent phonation and the ability to cough. Alternatively, heat and moisture exchange (HME) devices have been used in laryngectomized patients. We present an institutional quality improvement project exploring the use and efficacy of an HME device following tracheostomy.
Methods: Health care professionals and stakeholders from multiple disciplines were identified: otolaryngology, nursing, administration, case management, and speech-language pathology. The focus was on an otolaryngology acute care nursing unit. Protocols for product acquisition, nursing education, care flowcharts, and discharge planning were established. Efficacy was assessed by tracking patient pulmonary status, nursing notes, and questionnaires.
Results: Seventy-one tracheostomized patients were enrolled. Two patients (2.8%) were unable to tolerate the HME. There were no complications from mucous plugging or respiratory distress. Eighty-nine percent of nursing staff surveyed preferred the use of an HME device over CEHS, particularly for ease of patient mobility. Additional favorable findings were patient satisfaction, cost savings, reduced noise, communication, and ease of discharge education and planning.
Discussion: Replacing CEHS with HMEs provides distinct advantages, with a positive impact on patients, family members, and health care personnel. Resistance to changing from the traditional standard of care was alleviated with education, focused training, and positive outcomes.
Implications For Practice: These data indicate that an HME device is safe and offers advantages to both patients and nurses over traditional CEHS.
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http://dx.doi.org/10.1002/ohn.368 | DOI Listing |
Polymers (Basel)
August 2025
Key Laboratory of Marine Drugs, Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.
Background: Precision medicine refers to the formulation of personalized drug regimens according to the individual characteristics of patients to achieve optimal efficacy and minimize adverse reactions. Additive manufacturing (AM), also known as three-dimensional (3D) printing, has emerged as an optimal solution for precision drug delivery, enabling customizable and the fabrication of multifunctional structures with precise control over morphology and release behavior in pharmaceutics. However, the influence of 3D printing parameters on the printed tablets, especially regarding in vitro and in vivo performance, remains poorly understood, limiting the optimization of manufacturing processes for controlled-release profiles.
View Article and Find Full Text PDFNat Prod Res
July 2025
Faculty of Pharmacy, PHENIKAA University, Yen Nghia, Vietnam.
Hot melt extrusion (HME) technique has been discovered since the middle of XIX century, with the initial application of plastic and rubber industry. HME just expanded its range of application to pharmaceutical fields in 1970s, from then the target of HME application is almost on medical compounds/materials. Natural products (NPs) were already the main source contributed to the forming of pharmaceutical drugs/devices, but they are facing some fierce competition from artificial/synthesised substances/materials.
View Article and Find Full Text PDFAerosp Med Hum Perform
May 2025
Background: Patients with lung disease can experience hypoxemia on commercial aircraft, which can usually be corrected with supplementary oxygen. In some cases, combinations of medical conditions and inability to deliver oxygen via simple methods can complicate assessment and delivery of flight oxygen.
Case Report: A 53-yr-old woman with multiple comorbidities planned a 4-h commercial flight.
Auris Nasus Larynx
August 2025
Department of Otolaryngology-Head and Neck Surgery, Kobe University Hospital, Kobe 650-0017, Japan.
Objective: HMEs (Heat and Moisture Exchangers) are used postoperatively in laryngectomized patients to replace upper airway functions such as heating, humidification, filtration and resistance that are lost by the surgery. The clinical value of HME resistance function is controversial. There are no studies reporting actual measurements of air pressure generated by HMEs during breathing.
View Article and Find Full Text PDFRespir Care
June 2025
Dr. Lellouche, Ms. Cyr, and Mr. Bouchard are affiliated with Centre de Recherche, Institut Universitaire de Cardiologie et de Pneumologie de Québec-Université Laval, Québec, Canada.
The Sedaconda Anesthetic Conserving Device (ACD-S) is used for inhaled sedation in intubated patients and has passive humidification properties linked to the carbon material. However, limited evaluations of the hygrometric performance are available. The main aim of the study was to assess the humidification performance of this device with different ventilator settings and ambient temperatures.
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