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http://dx.doi.org/10.1016/S0140-6736(23)00444-0 | DOI Listing |
ISA Trans
September 2025
School of Mechatronic Engineering, Jiangsu Normal University, Xuzhou 221116, China. Electronic address:
Multi-arm rock drilling robots frequently encounter challenges in extreme environments, such as tunnels, where they are subjected to high-frequency impact loads, multi-degree-of-freedom motion coupling, and large-range motion control vibrations. First, we propose a collision-free path planning method that combines an improved genetic algorithm (IGA) and an improved artificial potential field method. This method is based on the kinematic model of the rock drilling robot.
View Article and Find Full Text PDFPhys Rev Lett
August 2025
University of Cambridge, DAMTP, Centre for Mathematical Sciences, Cambridge CB3 0WA, United Kingdom.
We study the elementary problem of moving an active particle by a trap with minimum work input. We show analytically that (open-loop) optimal protocols are not affected by activity, but work fluctuations are always increased. For closed-loop protocols, which rely on initial measurements of the self-propulsion, the average work has a minimum for a finite persistence time.
View Article and Find Full Text PDFJ Med Microbiol
September 2025
Alberta Precision Laboratories Public Health Lab, Edmonton, Alberta, Canada.
For thousands of years, parasitic infections have represented a constant challenge to human health. Despite constant progress in science and medicine, the challenge has remained mostly unchanged over the years, partly due to the vast complexity of the host-parasite-environment relationships. Over the last century, our approaches to these challenges have evolved through considerable advances in science and technology, offering new and better solutions.
View Article and Find Full Text PDFFront Neurosci
August 2025
First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
Background: Spinal cord injury (SCI) often leads to severe motor and sensory impairments, and current treatment methods have not achieved complete neural repair. In recent years, exosomes have become a research focus in the treatment of nerve injuries due to their important roles in intercellular information transfer, immune regulation, and neural repair. Our study conducts a scientometric analysis to map the research landscape related to exosomes in SCI.
View Article and Find Full Text PDFCNS Drugs
September 2025
Global Health Neurology Lab, Sydney, NSW, 2150, Australia.
Acute ischemic stroke (AIS) remains a leading cause of mortality and long-term disability globally, with survivors at high risk of recurrent stroke, cardiovascular events, and post-stroke dementia. Statins, while widely used for their lipid-lowering effects, also possess pleiotropic properties, including anti-inflammatory, endothelial-stabilizing, and neuroprotective actions, which may offer added benefit in AIS management. This article synthesizes emerging evidence on statins' dual mechanisms of action and evaluates their role in reducing recurrence, improving survival, and mitigating cognitive decline.
View Article and Find Full Text PDF