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Introduction: No clinical studies have examined the effect of mineral trioxide aggregate (MTA) obturation levels on the outcome of endodontic retreatment. This retrospective study examined treatment outcomes in three cohorts that compared overfilling, flush filling, and underfilling after orthograde retreatment using MTA.
Methods: Two hundred fifty patients with 264 teeth diagnosed with previously treated root canals and apical periodontitis retreated in a private endodontic practice were included. All teeth received MTA obturation and the extent of the final filling level was measured in relation to the major apical foramen. After 6-month follow-ups, all nonhealing cases were treated surgically. After 24- to 72-month reviews, the effect of preoperative lesion size and the degree of MTA obturation level were assessed. Multiple linear regression and time-to-event analysis using Stata 17 software (StataCorp LLC, College Station, TX) were used to evaluate the data.
Results: Within the three cohorts, 99 out of 108 overfilled teeth (91.7%), 90 out of 103 flush fills (87.4%), and 10 out of 53 underfilled teeth (18.9%) healed and were successfully retreated without surgery at 48-months. When surgical outcomes were included, the combined healed proportion was 93.2%. Preoperative lesion size was found to be an important predictor for retreatment nonhealing. A 1-mm increase in lesion size at baseline resulted in an estimated 11% (95% CI 1.04, 1.18)-38% (95% CI 1.22, 1.58) increase in the risk of surgery. Compared to overfilling and flush filling, underfilling was associated with an approximately three-fold increase in requiring surgery and characterized by delayed healing.
Conclusion: MTA obturation is a viable retreatment option for teeth with nonhealing endodontic treatment. MTA overfills or flush fillings do not adversely affect healing outcomes. However, MTA underfilling increases the chances for nonhealing and surgical intervention.
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http://dx.doi.org/10.1016/j.joen.2023.04.004 | DOI Listing |
Int Dent J
August 2025
Intercollaborative Endodontics and Engineering Research Group, Department of Operative Dentistry, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand. Electronic address:
Objectives: This study aimed to compare the percentage of volumetric changes between incompletely and completely set conditions of ProRoot MTA (MTA) and Endosequence Root Repair Material Fast-Set Putty (ERRM-FSP) as root-end filling materials in a simulated surgical environment.
Methods: Thirty-two human mandibular premolars with single, straight canals were selected. The canals were prepared and obturated with gutta-percha and AH-plus sealer.
J Conserv Dent Endod
July 2025
Department of Conservative Dentistry and Endodontics, Chhattisgarh Dental College and Research Institute, Rajnandgaon, Chhattisgarh, India.
Aims: The study aimed to evaluate and compare the efficacy of xylene in dissolving newer bioceramic sealers versus an epoxy resin-based sealer during endodontic retreatment.
Subjects And Methods: Comparing AH Plus to gutta-percha (GP) and CeraSeal (Meta Biomed), Prashanti Bioceramic Sealer, and MTA-Fillapex (Angelus), a total of 72 ( = 18) extracted human permanent teeth with a single root and a single canal were prepared to size F3 and obturated. The ProTaper Universal Retreatment technology was then used to retreat the canals.
BMC Oral Health
July 2025
Department of Endodontics, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Background: Complete removal of calcium silicate-based sealers (CSBSs) during root canal retreatment remains challenging, and the effect of chloroform on the bond strength of these materials remains unclear. This study aimed to evaluate the impact of different retreatment techniques on the dislocation resistance of gutta-percha and CSBS to root canal dentin.
Methods: Extracted single-rooted human teeth were prepared and filled via the single cone technique with gutta-percha and EndoSeal MTA (Maruchi, Wonju, Korea).
BMC Oral Health
July 2025
Department of Endodontics, Faculty of Dentistry, Zonguldak Bülent Ecevit University, Zonguldak, Turkey.
Background: Endodontic surgery is conducted when previous endodontic treatment has not succeeded, requiring a high level of technical precision. The success of these procedures is crucial for tooth prognosis. Sealing the root end cavity is one of the most important factors for the success of the procedure.
View Article and Find Full Text PDFJ Endod
July 2025
Dental Research Institute, Faculty of Dentistry, University of Toronto, Toronto, Ontario, Canada.
Introduction: This clinical investigation aims to determine and compare the volume, hardness, and elastic modulus of immature roots following regenerative endodontic treatment (RET) and mineral trioxide aggregate (MTA) apexification.
Methods: A total of six volunteers aged between 9 and 14 years participated in the study, each providing a pair of mandibular or maxillary premolars with normal pulp and periapex planned for extraction due to orthodontic reasons. After full pulpectomy, each pair received either an MTA obturation or RET using blood clot as scaffold, followed by permanent restoration.