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http://dx.doi.org/10.1016/j.jcjo.2023.02.013 | DOI Listing |
Surv Ophthalmol
September 2025
Yong Loo Lin School of Medicine, National University of Singapore, Singapore; National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore; Programme for Ocular Inflammation & Infection Translational Resear
The Choroidal Vascularity Index (CVI), derived from optical coherence tomography (OCT), has emerged as a potential biomarker for detecting vascular changes. Understanding its variability across physiological states, ocular conditions, and systemic diseases is crucial for its integration into clinical practice. We evaluated variations in CVI across different physiological states (e.
View Article and Find Full Text PDFAm J Ophthalmol
September 2025
Department of Ophthalmology, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address:
Objective: To examine the safety and effectiveness of non-inverted ILM Free Flap combined with the SPOT technique (Sub-Perfluorocarbon liquid (PFCL) injection of Ocular viscoelastic device (OVD) Technique) in the treatment of unclosed macular holes (MHs).
Design: Retrospective interventional case series.
Participants: Eight patients (8 eyes) with persistent unclosed MHs were treated at a tertiary eye hospital in China from September 2023 to February 2025.
Sci Adv
September 2025
Department of Ophthalmology, Mayo Clinic, Rochester, MN, USA.
Subretinal injection of adeno-associated virus (AAV) is generally more efficacious and less inflammatory than intravitreal injection for retinal gene therapy. However, adverse events (e.g.
View Article and Find Full Text PDFInfect Disord Drug Targets
August 2025
Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
Introduction: Preseptal cellulitis, the most common periorbital cellulitis manifestation, is more common in children. The aim of this cross-sectional study was to analyze the diagnosis and treatment of preseptal cellulitis infections in patients admitted to Children's Medical Center, an Ira-nian referral hospital, between 2015 and 2019.
Methods: The demographic characteristics of patients, symptoms at admission, affected eye (unilat-eral/bilateral and right/left), the duration of symptoms and treatment, imaging findings, and the mi-crobial culture were recorded from patient history and medical files.
Front Med (Lausanne)
August 2025
Department of Ophthalmology, The People's Hospital of Guangxi Zhuang Autonomous Region & Guangxi Key Laboratory of Eye Health & Guangxi Health Commission Key Laboratory of Ophthalmology and Related Systemic Diseases Artificial Intelligence Screening Technology & Institute of Ophthalmic Diseases, Gua
Purpose: To investigate the clinical manifestations and outcomes of herpes simplex keratitis (HSK) infection following corneal transplantation.
Methods: This retrospective study analyzed medical records of patients who underwent corneal transplantation at the People's Hospital of Guangxi Zhuang Autonomous Region between January 2018 and March 2024, with a minimum follow-up period of 1 year. The study examined post-transplantation herpes simplex virus (HSV) infections, including the timing of HSV infection, HSK classification, clinical manifestations, and outcomes.