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Background And Objectives: Aging in place (AIP) has been adopted as a key strategy to cope with the global public health challenge posed by population aging. The current study aimed to understand the association between older adult's AIP preference and various social and physical environmental factors at different scales.
Research Design And Methods: Following the ecological model of aging, this paper conducted a questionnaire survey of 827 independent-living older adults (60 years old and above) from four big cities in China's Yangtze River Delta region and employed a structural equation modeling method for analysis.
Results: Older adults from more developed cities exhibited a stronger preference for AIP than those from less developed cities. Individual characteristics, mental health, and physical health had a direct impact on AIP preference, whereas the effect of the community social environment was not significant. The perceived and objectively measured community-built environment indirectly affected AIP preference via mediation and chain effects.
Discussion And Implications: Complex paths affecting AIP preference were identified. At the city level, the social environment had a stronger influence than the physical environment on AIP, and the opposite pattern was observed at the community level. Mental health and physical health had opposite effects on AIP preference. Although physical health was negatively associated with AIP, age-friendly communities with compact, diverse, and accessible built environments have a positive impact on older adults' physical health and therefore should be promoted.
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http://dx.doi.org/10.1093/geroni/igad014 | DOI Listing |
J Clin Med
July 2025
Internal Medicine and Pediatrics, Department of Cardiology, Ghent University Hospital, 9000 Ghent, Belgium.
: Atrial fibrillation (AF) is a very common arrhythmia and the main cause of embolic events. Early diagnosis and treatment are crucial to prevent thromboembolic events. Although DOACs are an important advance in AF management, optimization is required.
View Article and Find Full Text PDFPathologie (Heidelb)
August 2025
Institut für Pathologie, Universitätsklinikum Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Despite advances in imaging diagnostics, the histological confirmation of suspected carcinoma through prostate core needle biopsy remains essential for treatment planning. Diagnosis is based on established morphological criteria such as architectural disturbances, cellular atypia, and loss of the basal cell layer. In addition to the most common acinar prostate carcinoma, various subtypes and rare histological patterns exist, which must be differentiated from benign mimickers.
View Article and Find Full Text PDFJ Thorac Oncol
June 2025
Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan.
Introduction: Up to 54% of all lung adenocarcinoma (LADC) cases in Asian populations occur in never-smoking women, suggesting that the impact of smoking and other environmental factors on the risk of early-onset LADC is minimal. Genetic factors may play a crucial role in disease development.
Methods: The prevalence of germline pathogenic variants (GPVs) of 454 hereditary cancer and DNA repair genes was evaluated by whole-exome and whole-genome sequencing of 348 early-onset LADC (aged ≤ 40 y) and 1425 later-onset LADC (aged ≥ 41 y) cases.
Curr Gastroenterol Rep
June 2025
Vatche and Tamar Manoukian Division of Digestive Diseases, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Purpose Of Review: Pouchitis is a common complication in patients with ulcerative colitis who undergo total colectomy with ileal pouch anal anastomosis that presents a challenge to clinicians. In the article, we review the management of patients with pouchitis based on best available evidence.
Recent Findings: Pouchitis can be practically classified into acute intermittent pouchitis (AIP), chronic antibiotic dependent pouchitis (CADP) and chronic antibiotic refractory pouchitis (CARP) based on the frequency of pouchitis episodes and response to antibiotics.
Cureus
April 2025
Geriatrics, University Hospital of Strasbourg, Strasbourg, FRA.
Biermer's disease is an autoimmune disorder characterized by atrophic gastritis leading to vitamin B12 deficiency, often revealed late due to non-specific symptoms. It may be associated with other autoimmune pathologies, notably Hashimoto's thyroiditis, as part of a type 3b autoimmune polyendocrinopathy (AIP). We report the case of a 44-year-old female patient, followed for autoimmune hypothyroidism, in whom vitamin B12 deficiency was detected.
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