Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Objectives: To evaluate the benefits of a novel dentin-bonding primer, namely, isocyanate-terminated urethane methacrylate precursor (UMP), which can form covalent bonds with demineralized dentin collagen.
Methods: The synthesized and purified UMP monomer was characterized and tested its effects on the degree of conversion (DC) and wettability of an acetone-based dental adhesive. Then UMP primers of different concentrations were formulated and used to prepare adhesive specimens, which were compared with solvent-treated groups. Primer-treated specimens with and without aging were also compared. To evaluate the bonding interface, microtensile strength tests, nano-indentation tests and nanoleakage- eavaluation were performed using a field-emission scanning electron microscope and nano-indenter. Data were analyzed using SPSS 20.0 software with significance set at α = 0.05 using one-way analysis of variance (ANOVA) and two-way ANOVA to characterize the effects of the primer.
Results: Treatment with the UMP primer promoted the DC and wettability of the adhesive on the demineralized dentin surface (P < 0.05); it also increased the bond strength of the aged dentin bonding interface (P < 0.05). Nanoleakage was reduced; the bonding interface became more stable, and the continuity and strength of the hybrid layer improved (P < 0.05) following UMP treatment. The application of 5 mM UMP as a primer for dentin bonding could lead to a stable bonding interface and long-lasting bonding effects.
Significance: The use of 5 mM UMP primer developed in this study could improve dentin bonding durability and has excellent clinical application prospects.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.dental.2023.03.008 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Demineralized Dentin Matrix Promotes Bone Regeneration Through IDO1-Mediated Th17/Treg Cell Balance Modulation.
Int Dent J
September 2025
Dept. of Oral Implantology, the Affiliated Stomatology Hospital of Kunming Medical University, Kunming, China. Electronic address:
Objectives: Demineralised dentin matrix (DDM) is an effective scaffold material for bone tissue engineering. However, the osteoimmunological mechanism of DDM remains unexplored. Th17/Treg cell balance has been noticed as a crucial factor in bone regeneration.
View Article and Find Full Text PDFSynergistic Effect of Enzymatic Deproteinization and Surface Pre-Reacted Glass Ionomer "SPRG" Fillers in self-etch adhesives: Boosting Anti-Demineralization and ABRZ.
J Dent
September 2025
Department of Restorative Dentistry, Faculty of Dentistry, Malaya University, Kuala Lumpur, Malaysia. Electronic address:
Objectives: to evaluate the effect of smear-layer deproteinization using papain gel and SPRG-adhesive on marginal-gap, anti-demineralization of enamel and dentin after chemical pH cycling and assess acid-base resistance zone (ABRZ) characteristics.
Methods: Cylindrical cavities were prepared cervically in thirty-two extracted premolars. Teeth were divided into two pretreatment groups (n=16); deproteinization with papain enzyme gel (Papacarie Due, Brazil) for 60 second, and no-deproteinization.
Histological evaluations of a series of socket preservation procedures using tooth as graft material.
Eur Rev Med Pharmacol Sci
August 2025
Private Practice.
Unlabelled: OBJECTIVE: In this multicenter study, we assessed the effectiveness of a novel autologous bone substitute obtained directly from the processing of extracted teeth. A total of 34 consecutive tooth grafting procedures were performed. MATERIALS AND METHODS: Immediately following atraumatic extraction for restorative or endodontic purposes, the bone defect was filled and covered with an Osseoguard© membrane, using autologous material derived from the extracted tooth.
View Article and Find Full Text PDFInhibition of MMP activity and preservation of dentin collagen structure of zinc-releasing glass ionomer cement.
J Dent
September 2025
Department of Cariology and Operative Dentistry, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan.
Objective: This study evaluated the ability of a novel zinc-releasing glass ionomer cement (GIC), Caredyne Restore (CR), to inhibit matrix metalloproteinase (MMP) activity and preserve dentin collagen integrity, compared with a conventional GIC (Fuji IX, FIX) and chlorhexidine (CHX), a widely used MMP inhibitor.
Methods: Demineralized bovine dentin beams were allocated to four groups: deionized water (negative control), CHX (positive control), FIX eluate, and CR eluate. MMP Activity was assessed before and after treatment using a colorimetric assay.
Re: 'Enhanced Bone Regeneration Using Demineralized Dentin Matrix: A Comparative Study in Alveolar Bone Repair'.
Int Dent J
September 2025
Dr. D.Y. Patil Vidyapeeth (Deemed to be University), Pimpri, Pune, Maharashtra, India.