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Recent advances in the cell structure regulation and performances improvement of porous poly(lactic acid) materials (PPMs) are systematically reviewed in this feature article. First, the typical processing methods, including template method, non-solvent induced phase separation, freeze-drying, and supercritical CO foaming, of PPMs are introduced emphatically. Their various cell morphologies by different processing methods are summarized: finger-like, honeycomb-like, fiber-like, through cell, open cell, closed cell, ball-like, and flower-like. Meanwhile, the transformation among different cell morphologies as well as the changes in cell size and cell density, having impact on the performances, is described. Second, the influence of stereo-complex crystals on the cell structure of PPMs is emphatically reviewed. Furthermore, the relationships between cell structure and properties that includes mechanical properties, thermal stability, heat insulation, and hydrophobicity, are elaborated. Eventually, the issues of PPMs worthy of further study are discussed.
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http://dx.doi.org/10.1002/marc.202300065 | DOI Listing |
Cytopathology
September 2025
Department of Cardiothoracic and Vascular Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India.
Mediastinal masses often present acutely as medical emergencies, necessitating prompt and accurate diagnosis. Imaging-guided fine needle aspiration cytology (FNAC) plays a pivotal role in rapidly identifying rare mediastinal tumours and differentiating them from other potential aetiologies, enabling timely intervention. Primary mediastinal germ cell tumours (PMGCTs) constitute approximately 15% of adult mediastinal neoplasms.
View Article and Find Full Text PDFProtein Cell
August 2025
Department of Neurology and National Center for Neurological Disorders, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, Shanghai 200433, China.
Cardiovascular disease (CVD) research is hindered by limited comprehensive analyses of plasma proteome across disease subtypes. Here, we systematically investigated the associations between plasma proteins and cardiovascular outcomes in 53,026 UK Biobank participants over a 14-year follow-up. Association analyses identified 3,089 significant associations involving 892 unique protein analytes across 13 CVD outcomes.
View Article and Find Full Text PDFBiol Lett
September 2025
Department of Science, Roma Tre University, Rome, Italy.
In the past decades, several authors have investigated the possibility that genome size is correlated with metabolic rates, obtaining conflicting results. The main biological explanation among the supporters of this correlation was related to the nucleotypic effect of the genome size, which, determining the cellular volume and hence the surface area-to-volume ratio, influences cellular metabolism. In the present study, I tested a different hypothesis: genome size, influencing red blood cell (RBC) volume, is correlated with capillary density and diameter.
View Article and Find Full Text PDFEur J Case Rep Intern Med
August 2025
Department of Gastroenterology, Staten Island University Hospital - Northwell Health, Staten Island, USA.
Unlabelled: Colorectal mucoceles are rare mucinous cysts arising in the gastrointestinal tract and presenting diagnostic and therapeutic challenges. We report the first successful treatment of an extraluminal colorectal mucocele using a lumen-apposing metal stent (LAMS). A 65-year-old male with a known medical history of diverticulitis treated with a partial colectomy presented with constipation and low back pain.
View Article and Find Full Text PDFRegen Biomater
August 2025
Institute of Stomatology & Oral Maxilla Facial Key Laboratory, First Medical Center of Chinese PLA General Hospital, Beijing 100853, China.
Reconstructing bone defects remains a significant challenge in clinical practice, driving the urgent need for advanced artificial grafts that simultaneously promote vascularization and osteogenesis. Addressing the critical trade-off between achieving high porosity/strength and effective bioactivity at safe ion doses, we incorporated strontium (Sr) into β-tricalcium phosphate (β-TCP) scaffolds with a triply periodic minimal surface (TPMS) structure using digital light processing (DLP)-based three-dimensional (3D) printing. Systematically screening Sr concentrations (0-10 mol%), we identified 10 mol% as optimal, leveraging the synergy between the biomimetic TPMS architecture, providing exceptional mechanical strength (up to 1.
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