Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064412PMC
http://dx.doi.org/10.7326/L23-0049DOI Listing

Publication Analysis

Top Keywords

update alert
4
alert risks
4
risks impact
4
impact angiotensin-converting
4
angiotensin-converting enzyme
4
enzyme inhibitors
4
inhibitors angiotensin-receptor
4
angiotensin-receptor blockers
4
blockers sars-cov-2
4
sars-cov-2 infection
4

Similar Publications

Background: Sacubitril/valsartan is a widely used cardiovascular agent characterized by its dual inhibition of the renin-angiotensin-aldosterone system and neprilysin. However, existing evidence on the safety of sacubitril/valsartan is primarily limited to clinical studies; this results in an inability to provide a timely update on associated adverse events.

Aim: To mine and systematically describe adverse events related to sacubitril/valsartan from September 2015 to June 2024 using the Food and Drug Administration Adverse Event Reporting System (FAERS) database.

View Article and Find Full Text PDF

Objectives: Quality control (QC) in clinical laboratory is critical to ensuring quality and accuracy of patient results. However, QC monitoring is complicated in the multi-analyte, multi-instrument assays common to biochemical genetics laboratories. Comprehensive off-the-shelf QC management systems optimized for such highly complex assays and platforms are relatively scarce.

View Article and Find Full Text PDF

Edge computing with federated learning for early detection of citric acid overdose and adjustment of regional citrate anticoagulation.

BMC Med Inform Decis Mak

August 2025

Department of Nephrology and Kidney Research Institute, West China Hospital, Sichuan University, No. 37 Guoxue Xiang, Chengdu, Sichuan, 610041, China.

Regional citrate anticoagulation (RCA) is critical for extracorporeal anticoagulation in continuous renal replacement therapy done at the bedside. To make patients' data more secure and to help with computer-based monitoring of dosages, we suggest a system that uses machine learning. This system will give early alerts about citric acid overdose and advise changes to how much citrate and calcium gluconate are infused into the patient's body.

View Article and Find Full Text PDF

It is critical to inform the public of the threat heat poses to health and provide actionable guidance on mitigating this risk before, during, and after heat events. To help educate the public during heat events, Health Canada works closely with Environment and Climate Change Canada (ECCC) to distribute heat-health messaging through a weather warning system. However, the warning system's current list of messages dates back over a decade.

View Article and Find Full Text PDF

A live attenuated chikungunya vaccine (IXCHIQ) received licensure in the United States (US) for ≥ 18-year-olds in November 2023. Post-licensure safety surveillance identified 28 adverse events in 2024 among US persons, including six neurological or cardiac serious adverse events (SAEs) in males ≥ 65 years. In early 2025, providers were alerted, a precaution for older persons was issued and vaccine guidance was updated.

View Article and Find Full Text PDF