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Vestibular schwannoma is the most common intracranial schwannoma and constitutes ~8% of all intracranial tumors in adults with an estimated incidence rate of ~1.3/100.000. Facial nerve schwannomas and cochlear nerve schwannomas are rare, and information regarding incidence rates of these is still missing in the literature. All three variants of nerve origin present most frequently with unilateral hearing loss, unilateral tinnitus and disequilibrium. Facial nerve palsy is a common finding in facial nerve schwannomas but a rare finding with vestibular schwannomas. The symptoms are normally persistent and often progress over time, leading to therapeutic interventions that predispose to quality of life-reducing morbidities, e.g., deafness and/or imbalance. The case report describes a 17-year-old male who, during a 1-month period, presented with profound unilateral hearing loss and severe facial nerve palsy followed by complete remission. An MRI scan showed a 5×8-mm schwannoma within the internal acoustic canal. Profound hearing loss together with concomitant severe peripheral facial nerve palsy in small schwannomas within the internal acoustic canal may show spontaneous and total remission within weeks of symptom debut. This knowledge, as well as possible remission of objective findings, should be considered before interventions with potential severe morbidity are suggested.
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http://dx.doi.org/10.3892/ol.2023.13712 | DOI Listing |
J Craniofac Surg
September 2025
Department of Otolaryngology-Head and Neck Surgery, Xijing Hospital, Air Force Military Medical University, Xi'an, China.
Salivary duct carcinoma (SDC) is a rare high-grade parotid malignancy prone to perineural spread. However, perineural spread of SDC has rarely been reported. The case of a 46-year-old male with SDC spread along the facial nerve (FN) is presented here.
View Article and Find Full Text PDFIEEE Trans Neural Syst Rehabil Eng
September 2025
Unilateral facial palsy, a common type of facial paralysis, profoundly impacts individuals' daily functionality and quality of life. The current clinical diagnosis of facial paralysis primarily relies on the subjective judgment of doctors, and the development of automated detection methods is challenged by the lack of publicly available facial paralysis datasets and the inability to analyze different facial nerve branches. To address these problems, we propose a new benchmark named UPFG-SG for Unilateral Peripheral Facial Paralysis Severity Grading.
View Article and Find Full Text PDFCureus
August 2025
Department of Neurosurgery, The University of Osaka Graduate School of Medicine, Suita, JPN.
Fungal cerebral aneurysms, particularly those resulting from direct invasion by fungal sinusitis, are rare and often fatal when involving the cavernous segment of the internal carotid artery (ICA). We present a case of a ruptured fungal ICA aneurysm caused by sinusitis, successfully treated with parent artery occlusion (PAO). In this case, an 80-year-old woman presented with right ptosis, facial pain, and cranial nerve III, IV, and VI palsies.
View Article and Find Full Text PDFJ Mater Chem B
September 2025
Nebraska Translational Research Center (NTRC), Department of Growth and Development, College of Dentistry, University of Nebraska Medical Center, Joseph D. & Millie E. Williams Science Hall, 525 S 42nd St, Room No 3.0.010, Omaha, NE 68105-6040, USA.
Facial nerve injuries cause significant functional impairments, affect facial expressions, speech, and overall quality of life. This article explores advances in facial nerve regeneration, encompassing both conventional and emerging therapeutic strategies. The regenerative process involves Wallerian degeneration, axonal regrowth, and target muscle reinnervation, where the distal axon degrades and the proximal axon initiates sprouting to restore connectivity.
View Article and Find Full Text PDFOral Maxillofac Surg
September 2025
Department of Otolaryngology, Head and Neck Surgery, Kansai Medical University, Shinmachi 2-5-1, Hirakata-city, Osaka, Japan.
Purpose: For submandibular gland resection, conventional surgery with the naked eye remains the standard. With its excellent automatic focus and high magnification, the ORBEYE 3D exoscope enables precise submandibular gland resection with less stress. Therefore, we aimed to examine the usefulness of the exoscope in submandibular gland resection.
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