Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Since being FDA approved in 1984, cochlear implantation has been used successfully to restore hearing in those with severe to profound hearing loss with broader applications including single-sided deafness, the use of hybrid electroacoustic stimulation, and implantation at all extremes of age. Cochlear implants have undergone multiple changes in the design aimed at improving the processing technology, while simultaneously minimizing the surgical trauma and foreign body reaction. The following review examines the human temporal bone studies regarding the anatomy of the human cochlea and how the anatomy relates to cochlear implant design, the factors related to complications after implantation, and the predictors of new tissue formation and osteoneogenesis. Histopathological studies are reviewed which aim to understand the potential implications of the effects of new tissue formation and inflammation following implantation.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9959196PMC
http://dx.doi.org/10.3390/jpm13020352DOI Listing

Publication Analysis

Top Keywords

human temporal
8
temporal bone
8
histopathological studies
8
cochlear implantation
8
tissue formation
8
implantation
5
archival human
4
bone anatomical
4
anatomical histopathological
4
cochlear
4

Similar Publications

Individual alpha frequency tACS modifies the detection of space-time optical illusion.

Exp Brain Res

September 2025

Siena Brain Investigation and Neuromodulation Lab (Si-BIN Lab), Department of Medicine, Surgery and Neuroscience, Neurology and Clinical Neurophysiology Section, University of Siena, Siena, Italy.

Postdiction is a perceptual phenomenon where the perception of an earlier stimulus is influenced by a later one. This effect is commonly studied using the 'rabbit illusion', in which temporally regular, but spatially irregular, stimuli are perceived as equidistant. While previous research has focused on short inter-stimulus intervals (100-200 ms), the role of longer intervals, which may engage late attentional processes, remains unexplored.

View Article and Find Full Text PDF

Purpose: Percutaneous nephrolithotomy (PCNL) is a common technique in the surgical management of renal lithiasis, but it also represents a significant workload for surgeons. Factors such as the patient's position and the type of lithotripter used influence the physical and mental load on the surgeon. The study aimed to identify stressors related to PCNL by comparing the physical and mental workload experienced by urologists during PCNL under different patient positions and using two lithotripters.

View Article and Find Full Text PDF

The advantage of periodic over constant signalling in microRNA-mediated regulation.

Nucleic Acids Res

September 2025

Department of Applied Science and Technology, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Torino, Italy.

Cells may exploit oscillatory gene expression to encode biological information. Temporal features of oscillations, such as pulse frequency and amplitude, are determinant for the outcome of signalling pathways. However, little effort has been devoted to unveiling the role of pulsatility in the context of post-transcriptional gene regulation, where microRNAs act by binding to RNAs and regulate their expression.

View Article and Find Full Text PDF

Introduction: Facial aging is a multifactorial process characterized by skin laxity, volume loss, and collagen degradation. Calcium Hydroxyapatite (CaHA) is a versatile biostimulatory filler that can provide both structural support and collagen stimulation. This study evaluates a novel technique using CaHA with tailored dilutions for minimally invasive facial rejuvenation, focusing on key ligamentous structures.

View Article and Find Full Text PDF

Hepatitis B virus (HBV) infection is a global health challenge, with the World Health Organization (WHO) targeting its elimination by 2030. Jordan lacks sufficient data on HBV epidemiology, including prevalence, incidence and clearance. This study addresses these gaps through a retrospective analysis of HBV testing data from 40,268 individuals collected at Biolab Diagnostic Laboratories (2010-2024).

View Article and Find Full Text PDF